7p4h
From Proteopedia
(Difference between revisions)
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<StructureSection load='7p4h' size='340' side='right'caption='[[7p4h]], [[Resolution|resolution]] 2.10Å' scene=''> | <StructureSection load='7p4h' size='340' side='right'caption='[[7p4h]], [[Resolution|resolution]] 2.10Å' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
| - | <table><tr><td colspan='2'> | + | <table><tr><td colspan='2'>Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7P4H OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7P4H FirstGlance]. <br> |
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.1Å</td></tr> | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.1Å</td></tr> | ||
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=5IH:3,4-dimethyl-7-[[(3~{S})-piperidin-3-yl]methoxy]chromen-2-one'>5IH</scene>, <scene name='pdbligand=C15:N-DODECYL-N,N-DIMETHYL-3-AMMONIO-1-PROPANESULFONATE'>C15</scene>, <scene name='pdbligand=FAD:FLAVIN-ADENINE+DINUCLEOTIDE'>FAD</scene></td></tr> | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=5IH:3,4-dimethyl-7-[[(3~{S})-piperidin-3-yl]methoxy]chromen-2-one'>5IH</scene>, <scene name='pdbligand=C15:N-DODECYL-N,N-DIMETHYL-3-AMMONIO-1-PROPANESULFONATE'>C15</scene>, <scene name='pdbligand=FAD:FLAVIN-ADENINE+DINUCLEOTIDE'>FAD</scene></td></tr> | ||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7p4h FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7p4h OCA], [https://pdbe.org/7p4h PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7p4h RCSB], [https://www.ebi.ac.uk/pdbsum/7p4h PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7p4h ProSAT]</span></td></tr> | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7p4h FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7p4h OCA], [https://pdbe.org/7p4h PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7p4h RCSB], [https://www.ebi.ac.uk/pdbsum/7p4h PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7p4h ProSAT]</span></td></tr> | ||
</table> | </table> | ||
| - | == Function == | ||
| - | [https://www.uniprot.org/uniprot/AOFB_HUMAN AOFB_HUMAN] Catalyzes the oxidative deamination of biogenic and xenobiotic amines and has important functions in the metabolism of neuroactive and vasoactive amines in the central nervous system and peripheral tissues. MAOB preferentially degrades benzylamine and phenylethylamine. | ||
<div style="background-color:#fffaf0;"> | <div style="background-color:#fffaf0;"> | ||
== Publication Abstract from PubMed == | == Publication Abstract from PubMed == | ||
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__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
| - | [[Category: Homo sapiens]] | ||
[[Category: Large Structures]] | [[Category: Large Structures]] | ||
[[Category: Binda C]] | [[Category: Binda C]] | ||
[[Category: Iacovino LG]] | [[Category: Iacovino LG]] | ||
[[Category: Pisani L]] | [[Category: Pisani L]] | ||
Current revision
Crystal Structure of Monoamine Oxidase B in complex with inhibitor (+)-2
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