8bhz
From Proteopedia
(Difference between revisions)
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| - | ==The apo-crystal structure of a variant form of the 28-kDa Schistosoma | + | ==The apo-crystal structure of a variant form of the 28-kDa Schistosoma bovis glutathione transferase in orthorhombic form== |
<StructureSection load='8bhz' size='340' side='right'caption='[[8bhz]], [[Resolution|resolution]] 2.40Å' scene=''> | <StructureSection load='8bhz' size='340' side='right'caption='[[8bhz]], [[Resolution|resolution]] 2.40Å' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
| - | <table><tr><td colspan='2'>[[8bhz]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/ | + | <table><tr><td colspan='2'>[[8bhz]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Schistosoma_bovis Schistosoma bovis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=8BHZ OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=8BHZ FirstGlance]. <br> |
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.4Å</td></tr> | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.4Å</td></tr> | ||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=8bhz FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=8bhz OCA], [https://pdbe.org/8bhz PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=8bhz RCSB], [https://www.ebi.ac.uk/pdbsum/8bhz PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=8bhz ProSAT]</span></td></tr> | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=8bhz FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=8bhz OCA], [https://pdbe.org/8bhz PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=8bhz RCSB], [https://www.ebi.ac.uk/pdbsum/8bhz PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=8bhz ProSAT]</span></td></tr> | ||
</table> | </table> | ||
== Function == | == Function == | ||
| - | [https://www.uniprot.org/uniprot/ | + | [https://www.uniprot.org/uniprot/GST28_SCHBO GST28_SCHBO] Conjugation of reduced glutathione to a wide number of exogenous and endogenous hydrophobic electrophiles. GST isoenzymes appear to play a central role in the parasite detoxification system. Other functions are also suspected including a role in increasing the solubility of haematin in the parasite gut. |
==See Also== | ==See Also== | ||
*[[Glutathione S-transferase 3D structures|Glutathione S-transferase 3D structures]] | *[[Glutathione S-transferase 3D structures|Glutathione S-transferase 3D structures]] | ||
| - | == References == | ||
| - | <references/> | ||
__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
[[Category: Large Structures]] | [[Category: Large Structures]] | ||
| - | [[Category: Schistosoma | + | [[Category: Schistosoma bovis]] |
[[Category: Achilonu IA]] | [[Category: Achilonu IA]] | ||
[[Category: Mfeka SM]] | [[Category: Mfeka SM]] | ||
Current revision
The apo-crystal structure of a variant form of the 28-kDa Schistosoma bovis glutathione transferase in orthorhombic form
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