Tyrosine kinase 3D structures
From Proteopedia
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**[[2kk1]] – hTK C terminal – NMR<BR /> | **[[2kk1]] – hTK C terminal – NMR<BR /> | ||
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| - | *'''Anaplastic lymphoma kinase (Alk)''' or Alk tyrosine kinae receptor; Domains – Gly-rich 678-986; TG+EGF=like 648-1030; kinase 1093-1411 | ||
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| - | **[[4tt7]], [[6cdt]] - hTK kinase domain<br /> | ||
| - | **[[2yhv]], [[2yjr]], [[2yjs]], [[3l9p]], [[3lcs]], [[3lct]], [[4anl]], [[4fnw]], [[4fnx]] - hTK kinase domain (mutant)<br /> | ||
| - | **[[7lrz]], [[7mzw]], [[7mzy]] - hTK Gly-rich domain<br /> | ||
| - | **[[7nx4]] - hTK TG+EGF-like domain<br /> | ||
| - | **[[7nx3]] - hTK TG+EGF-like domain + antibody<br /> | ||
| - | **[[2xb7]], [[2xba]], [[3aox]], [[4ccb]], [[4ccu]], [[4cli]], [[4cmo]], [[4cmt]], [[4cmu]], [[4cnh]], [[4ctb]], [[4ctc]], [[5imx]], [[5kz0]], [[6edl]], [[6ebw]], [[6e0r]], [[6mx8]], [[7btt]], [[7jy4]], [[7jyr]], [[7jys]], [[7jyt]], [[8arj]] - hTK kinase domain + inhibitor<br /> | ||
| - | **[[4dce]], [[4fob]], [[4foc]], [[4fod]], [[4fny]], [[4fnz]], [[4joa]], [[4mkc]], [[4z55]], [[5iug]], [[5iuh]], [[5iui]], [[4cd0]], [[4clj]] - hTK kinase domain (mutant) + inhibitor<br /> | ||
| - | **[[2xp2]], [[5j7h]], [[5fto]], [[5ftq]], [[7r7k]], [[7r7r]] - hTK kinase domain + cancer drug<br /> | ||
| - | **[[2yfx]], [[4anq]], [[4ans]], [[5aaa]], [[5aab]], [[5aac]], [[5a9u]], [[5aa8]], [[5aa9]] - hTK kinase domain (mutant) + cancer drug<br /> | ||
| - | **[[7n00], [[7nwz]]] - hTK kinase domain (mutant) + AUG-alpha<br /> | ||
| - | **[[7ls0]] - hTK kinase domain/AUG-alpha<br /> | ||
*'''Csk tyrosine kinase''' | *'''Csk tyrosine kinase''' | ||
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**[[4le9]], [[4oml]], [[4omm]], [[4omn]], [[4omo]], [[4omp]], [[4omq]], [[4rtu]], [[4rtx]], [[5i11]], [[7a30]], [[7a31]], [[7a32]], [[7a33]], [[7a34]], [[7a35]], [[7a36]], [[7a37]], [[7a38]], [[7a39]], [[7a3a]], [[7a3b]], [[7a3c]], [[7a3d]], [[7a3e]], [[7ner]], [[7nes]], [[7net]] - cTK (mutant) <br /> | **[[4le9]], [[4oml]], [[4omm]], [[4omn]], [[4omo]], [[4omp]], [[4omq]], [[4rtu]], [[4rtx]], [[5i11]], [[7a30]], [[7a31]], [[7a32]], [[7a33]], [[7a34]], [[7a35]], [[7a36]], [[7a37]], [[7a38]], [[7a39]], [[7a3a]], [[7a3b]], [[7a3c]], [[7a3d]], [[7a3e]], [[7ner]], [[7nes]], [[7net]] - cTK (mutant) <br /> | ||
**[[6xx3]], [[6xx2]], [[6xx5]], [[6xx4]], [[6xx5]], [[6xx2]] - cTK (mutant) + ion<br /> | **[[6xx3]], [[6xx2]], [[6xx5]], [[6xx4]], [[6xx5]], [[6xx2]] - cTK (mutant) + ion<br /> | ||
| - | **[[ | + | **[[2pri]], [[4hxj]], [[4qt7]], [[4rty]], [[4rtz]] - cTK + peptide<br /> |
**[[1prm]], [[1rlp]], [[1rlq]], [[1nlo]], [[1nlp]] - cTK + peptide - NMR<br /> | **[[1prm]], [[1rlp]], [[1rlq]], [[1nlo]], [[1nlp]] - cTK + peptide - NMR<br /> | ||
**[[4hvu]], [[4hvv]], [[4hvw]], [[4rtv]], [[4rtw]], [[5ob2]], [[5ob1]], [[5ob0]], [[5oav]] - cTK (mutant) + peptide<br /> | **[[4hvu]], [[4hvv]], [[4hvw]], [[4rtv]], [[4rtw]], [[5ob2]], [[5ob1]], [[5ob0]], [[5oav]] - cTK (mutant) + peptide<br /> | ||
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*'''ErbB tyrosine kinase''' see [[Epidermal Growth Factor Receptor]] | *'''ErbB tyrosine kinase''' see [[Epidermal Growth Factor Receptor]] | ||
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| - | *'''MuSK tyrosine kinase''' | ||
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| - | **[[3hkl]] - rTK MuSK Fz-Crd domain <br /> | ||
| - | **[[1luf]], [[2iep]] - rTK MuSK cytoplasmic domain <br /> | ||
*'''Sgk223 tyrosine kinase or sugen kinase''' | *'''Sgk223 tyrosine kinase or sugen kinase''' | ||
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**[[1fvr]] - hTK Tie2 kinase domain <br /> | **[[1fvr]] - hTK Tie2 kinase domain <br /> | ||
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| - | *'''Ret tyrosine kinase''' or proto-oncogene tyrosine protein kinase receptor Ret | ||
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| - | **[[6nja]] - hTK Ret kinase domain<br /> | ||
| - | **[[6fek]] - hTK Ret kinase domain (mutant)<br /> | ||
| - | **[[5amn]], [[6vhg]], [[7run]] - hTK Ret kinase domain + inhibitor<br /> | ||
| - | **[[6i82]], [[6i83]] - hTK Ret kinase domain (mutant) + inhibitor<br /> | ||
| - | **[[6ne7]], [[6nec]], [[7ju5]], [[7ju6]] - hTK Ret kinase domain + cancer drug<br /> | ||
| - | **[[4ux8]] - hTK Ret extracellular domain + GFR alpha 1<br /> | ||
*'''DDR1 and DDR2 tyrosine kinase receptors''' see [[Epithelial discoidin domain-containing receptor]] | *'''DDR1 and DDR2 tyrosine kinase receptors''' see [[Epithelial discoidin domain-containing receptor]] | ||
Current revision
3D structures of tyrosine kinase
Updated on 01-March-2024 - For a general description of the protein see Tyrosine kinase
