8rbd
From Proteopedia
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| - | '''Unreleased structure''' | ||
| - | + | ==Crystal structure of Mycobacterium tuberculosis MmaA1 with Sinefungin (SFG)== | |
| - | + | <StructureSection load='8rbd' size='340' side='right'caption='[[8rbd]], [[Resolution|resolution]] 1.50Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[8rbd]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Mycobacterium_tuberculosis Mycobacterium tuberculosis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=8RBD OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=8RBD FirstGlance]. <br> | |
| - | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.5Å</td></tr> | |
| - | [[Category: | + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CSO:S-HYDROXYCYSTEINE'>CSO</scene>, <scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=SFG:SINEFUNGIN'>SFG</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr> |
| + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=8rbd FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=8rbd OCA], [https://pdbe.org/8rbd PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=8rbd RCSB], [https://www.ebi.ac.uk/pdbsum/8rbd PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=8rbd ProSAT]</span></td></tr> | ||
| + | </table> | ||
| + | == Function == | ||
| + | [https://www.uniprot.org/uniprot/MMAA1_MYCBO MMAA1_MYCBO] Involved in the conversion of a cis-olefin into a trans-olefin with concomitant introduction of an allylic methyl branch at the proximal position of the precursor to both the methoxy and ketomycolic acids. It directly affects the cis- to trans ratio and indirectly affects the keto to methoxy ratio (By similarity). | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
| + | [[Category: Large Structures]] | ||
| + | [[Category: Mycobacterium tuberculosis]] | ||
| + | [[Category: Chaudhary B]] | ||
| + | [[Category: Dong G]] | ||
| + | [[Category: Kobakhidze G]] | ||
| + | [[Category: Madhurantakam G]] | ||
| + | [[Category: Mazumdar PA]] | ||
| + | [[Category: Wachelder L]] | ||
Current revision
Crystal structure of Mycobacterium tuberculosis MmaA1 with Sinefungin (SFG)
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