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8vy8
From Proteopedia
(Difference between revisions)
(New page: '''Unreleased structure''' The entry 8vy8 is ON HOLD Authors: Xu, J., Lei, X., Chen, L. Description: Recombinant alpha bungarotoxin complexed with HAP peptide [[Category: Unreleased St...) |
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| - | '''Unreleased structure''' | ||
| - | + | ==Recombinant alpha bungarotoxin complexed with HAP peptide== | |
| - | + | <StructureSection load='8vy8' size='340' side='right'caption='[[8vy8]], [[Resolution|resolution]] 2.40Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[8vy8]] is a 8 chain structure with sequence from [https://en.wikipedia.org/wiki/Bungarus_multicinctus Bungarus multicinctus] and [https://en.wikipedia.org/wiki/Synthetic_construct Synthetic construct]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=8VY8 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=8VY8 FirstGlance]. <br> | |
| - | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.4Å</td></tr> | |
| - | [[Category: | + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=EPE:4-(2-HYDROXYETHYL)-1-PIPERAZINE+ETHANESULFONIC+ACID'>EPE</scene></td></tr> |
| - | [[Category: | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=8vy8 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=8vy8 OCA], [https://pdbe.org/8vy8 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=8vy8 RCSB], [https://www.ebi.ac.uk/pdbsum/8vy8 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=8vy8 ProSAT]</span></td></tr> |
| - | [[Category: Lei | + | </table> |
| - | [[Category: | + | == Function == |
| + | [https://www.uniprot.org/uniprot/3L21V_BUNMU 3L21V_BUNMU] Binds with high affinity to muscular (alpha-1/CHRNA1) and neuronal (alpha-7/CHRNA7) nicotinic acetylcholine receptor (nAChR) and inhibits acetylcholine from binding to the receptor, thereby impairing neuromuscular and neuronal transmission.[UniProtKB:P60615]<ref>PMID:10497260</ref> | ||
| + | == References == | ||
| + | <references/> | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
| + | [[Category: Bungarus multicinctus]] | ||
| + | [[Category: Large Structures]] | ||
| + | [[Category: Synthetic construct]] | ||
| + | [[Category: Chen L]] | ||
| + | [[Category: Lei X]] | ||
| + | [[Category: Xu J]] | ||
Current revision
Recombinant alpha bungarotoxin complexed with HAP peptide
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