We apologize for Proteopedia being slow to respond. For the past two years, a new implementation of Proteopedia has been being built. Soon, it will replace this 18-year old system. All existing content will be moved to the new system at a date that will be announced here.
8y6n
From Proteopedia
(Difference between revisions)
(New page: '''Unreleased structure''' The entry 8y6n is ON HOLD Authors: Description: Category: Unreleased Structures) |
|||
| (2 intermediate revisions not shown.) | |||
| Line 1: | Line 1: | ||
| - | '''Unreleased structure''' | ||
| - | The | + | ==The structure of Oryza sativa HKT1;5 salt tolerant variant== |
| + | <StructureSection load='8y6n' size='340' side='right'caption='[[8y6n]], [[Resolution|resolution]] 3.40Å' scene=''> | ||
| + | == Structural highlights == | ||
| + | <table><tr><td colspan='2'>[[8y6n]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli] and [https://en.wikipedia.org/wiki/Oryza_sativa Oryza sativa]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=8Y6N OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=8Y6N FirstGlance]. <br> | ||
| + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Electron Microscopy, [[Resolution|Resolution]] 3.4Å</td></tr> | ||
| + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=8y6n FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=8y6n OCA], [https://pdbe.org/8y6n PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=8y6n RCSB], [https://www.ebi.ac.uk/pdbsum/8y6n PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=8y6n ProSAT]</span></td></tr> | ||
| + | </table> | ||
| + | == Function == | ||
| + | [https://www.uniprot.org/uniprot/C562_ECOLX C562_ECOLX] Electron-transport protein of unknown function.[https://www.uniprot.org/uniprot/M1G2X2_ORYSA M1G2X2_ORYSA] | ||
| + | <div style="background-color:#fffaf0;"> | ||
| + | == Publication Abstract from PubMed == | ||
| + | The high-affinity potassium transporters (HKTs), selectively permeable to either Na(+) alone or Na(+)/K(+), play pivotal roles in maintaining plant Na(+)/K(+) homeostasis. Although their involvement in salt tolerance is widely reported, the molecular underpinnings of Oryza sativa HKTs remain elusive. In this study, we elucidate the structures of OsHKT1;1 and OsHKT2;1, representing two distinct classes of rice HKTs. The dimeric assembled OsHKTs can be structurally divided into four domains. At the dimer interface, a half-helix or a loop in the third domain is coordinated by the C-terminal region of the opposite subunit. Additionally, we present the structures of OsHKT1;5 salt-tolerant and salt-sensitive variants, a key quantitative trait locus associated with salt tolerance. The salt-tolerant variant of OsHKT1;5 exhibits enhanced Na(+) transport capability and displays a more flexible conformation. These findings shed light on the molecular basis of rice HKTs and provide insights into their role in salt tolerance. | ||
| - | + | Structural insights into the Oryza sativa cation transporters HKTs in salt tolerance.,Gao R, Jia Y, Xu X, Fu P, Zhou J, Yang G J Integr Plant Biol. 2024 Apr;66(4):700-708. doi: 10.1111/jipb.13632. Epub 2024 , Feb 26. PMID:38409933<ref>PMID:38409933</ref> | |
| - | + | From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br> | |
| - | [[Category: | + | </div> |
| + | <div class="pdbe-citations 8y6n" style="background-color:#fffaf0;"></div> | ||
| + | == References == | ||
| + | <references/> | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
| + | [[Category: Escherichia coli]] | ||
| + | [[Category: Large Structures]] | ||
| + | [[Category: Oryza sativa]] | ||
| + | [[Category: Gao R]] | ||
| + | [[Category: Yang GH]] | ||
Current revision
The structure of Oryza sativa HKT1;5 salt tolerant variant
| |||||||||||
