8y85
From Proteopedia
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- | '''Unreleased structure''' | ||
- | + | ==Human AE3 with NaHCO3- and DIDS== | |
- | + | <StructureSection load='8y85' size='340' side='right'caption='[[8y85]], [[Resolution|resolution]] 2.73Å' scene=''> | |
- | + | == Structural highlights == | |
- | + | <table><tr><td colspan='2'>[[8y85]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=8Y85 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=8Y85 FirstGlance]. <br> | |
- | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Electron Microscopy, [[Resolution|Resolution]] 2.73Å</td></tr> | |
- | [[Category: | + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=4KU:2,2-ETHANE-1,2-DIYLBIS{5-[(SULFANYLMETHYL)AMINO]BENZENESULFONIC+ACID}'>4KU</scene>, <scene name='pdbligand=BCT:BICARBONATE+ION'>BCT</scene></td></tr> |
+ | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=8y85 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=8y85 OCA], [https://pdbe.org/8y85 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=8y85 RCSB], [https://www.ebi.ac.uk/pdbsum/8y85 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=8y85 ProSAT]</span></td></tr> | ||
+ | </table> | ||
+ | == Disease == | ||
+ | [https://www.uniprot.org/uniprot/B3A3_HUMAN B3A3_HUMAN] Familial short QT syndrome. The disease is caused by variants affecting the gene represented in this entry. | ||
+ | == Function == | ||
+ | [https://www.uniprot.org/uniprot/B3A3_HUMAN B3A3_HUMAN] Sodium-independent anion exchanger which mediates the electroneutral exchange of chloride for bicarbonate ions across the cell membrane (PubMed:29167417, PubMed:7923606). May be involved in the regulation of intracellular pH, and the modulation of cardiac action potential (PubMed:29167417).<ref>PMID:29167417</ref> <ref>PMID:7923606</ref> | ||
+ | == References == | ||
+ | <references/> | ||
+ | __TOC__ | ||
+ | </StructureSection> | ||
+ | [[Category: Homo sapiens]] | ||
+ | [[Category: Large Structures]] | ||
+ | [[Category: Cao Y]] | ||
+ | [[Category: Jian L]] | ||
+ | [[Category: Qin A]] | ||
+ | [[Category: Wang Q]] | ||
+ | [[Category: Xia Y]] | ||
+ | [[Category: Yao D]] | ||
+ | [[Category: Zhang Q]] |
Current revision
Human AE3 with NaHCO3- and DIDS
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Categories: Homo sapiens | Large Structures | Cao Y | Jian L | Qin A | Wang Q | Xia Y | Yao D | Zhang Q