1q7o

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[[Image:1q7o.jpg|left|200px]]
 
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==Determination of f-MLF-OH Peptide Structure with solid-state magic-angle spinning NMR Spectroscopy==
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The line below this paragraph, containing "STRUCTURE_1q7o", creates the "Structure Box" on the page.
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<StructureSection load='1q7o' size='340' side='right'caption='[[1q7o]]' scene=''>
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You may change the PDB parameter (which sets the PDB file loaded into the applet)
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== Structural highlights ==
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or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
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<table><tr><td colspan='2'>[[1q7o]] is a 1 chain structure. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1Q7O OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1Q7O FirstGlance]. <br>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Solid-state NMR</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=FME:N-FORMYLMETHIONINE'>FME</scene>, <scene name='pdbligand=MTY:META-TYROSINE'>MTY</scene></td></tr>
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{{STRUCTURE_1q7o| PDB=1q7o | SCENE= }}
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1q7o FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1q7o OCA], [https://pdbe.org/1q7o PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1q7o RCSB], [https://www.ebi.ac.uk/pdbsum/1q7o PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1q7o ProSAT]</span></td></tr>
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</table>
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'''Determination of f-MLF-OH Peptide Structure with solid-state magic-angle spinning NMR Spectroscopy'''
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<div style="background-color:#fffaf0;">
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== Publication Abstract from PubMed ==
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==Overview==
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The three-dimensional structure of the chemotactic peptide N-formyl-l-Met-l-Leu-l-Phe-OH was determined by using solid-state NMR (SSNMR). The set of SSNMR data consisted of 16 (13)C-(15)N distances and 18 torsion angle constraints (on 10 angles), recorded from uniformly (13)C,(15)N- and (15)N-labeled samples. The peptide's structure was calculated by means of simulated annealing and a newly developed protocol that ensures that all of conformational space, consistent with the structural constraints, is searched completely. The result is a high-quality structure of a molecule that has thus far not been amenable to single-crystal diffraction studies. The extensions of the SSNMR techniques and computational methods to larger systems appear promising.
The three-dimensional structure of the chemotactic peptide N-formyl-l-Met-l-Leu-l-Phe-OH was determined by using solid-state NMR (SSNMR). The set of SSNMR data consisted of 16 (13)C-(15)N distances and 18 torsion angle constraints (on 10 angles), recorded from uniformly (13)C,(15)N- and (15)N-labeled samples. The peptide's structure was calculated by means of simulated annealing and a newly developed protocol that ensures that all of conformational space, consistent with the structural constraints, is searched completely. The result is a high-quality structure of a molecule that has thus far not been amenable to single-crystal diffraction studies. The extensions of the SSNMR techniques and computational methods to larger systems appear promising.
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==About this Structure==
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De novo determination of peptide structure with solid-state magic-angle spinning NMR spectroscopy.,Rienstra CM, Tucker-Kellogg L, Jaroniec CP, Hohwy M, Reif B, McMahon MT, Tidor B, Lozano-Perez T, Griffin RG Proc Natl Acad Sci U S A. 2002 Aug 6;99(16):10260-5. Epub 2002 Jul 29. PMID:12149447<ref>PMID:12149447</ref>
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Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1Q7O OCA].
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==Reference==
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From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
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De novo determination of peptide structure with solid-state magic-angle spinning NMR spectroscopy., Rienstra CM, Tucker-Kellogg L, Jaroniec CP, Hohwy M, Reif B, McMahon MT, Tidor B, Lozano-Perez T, Griffin RG, Proc Natl Acad Sci U S A. 2002 Aug 6;99(16):10260-5. Epub 2002 Jul 29. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/12149447 12149447]
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</div>
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[[Category: Griffin, R G.]]
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<div class="pdbe-citations 1q7o" style="background-color:#fffaf0;"></div>
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[[Category: Hohwy, M.]]
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== References ==
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[[Category: Jaroniec, C P.]]
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<references/>
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[[Category: Lozano-Perez, T.]]
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__TOC__
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[[Category: McMahon, M T.]]
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</StructureSection>
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[[Category: Reif, B.]]
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[[Category: Large Structures]]
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[[Category: Rienstra, C M.]]
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[[Category: Griffin RG]]
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[[Category: Tidor, B.]]
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[[Category: Hohwy M]]
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[[Category: Tucker-Kellogg, L.]]
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[[Category: Jaroniec CP]]
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[[Category: Chemotactic peptide]]
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[[Category: Lozano-Perez T]]
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[[Category: Mlf]]
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[[Category: McMahon MT]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sat May 3 05:58:13 2008''
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[[Category: Reif B]]
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[[Category: Rienstra CM]]
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[[Category: Tidor B]]
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[[Category: Tucker-Kellogg L]]

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Determination of f-MLF-OH Peptide Structure with solid-state magic-angle spinning NMR Spectroscopy

PDB ID 1q7o

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