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Tyrosine phosphatase 3D structures

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**[[8u1e]] - hPTP-1b catalytic domain - human<br />
**[[8u1e]] - hPTP-1b catalytic domain - human<br />
-
**[[1a5y]], [[2hnp]], [[2hnq]], [[1oem]], [[1oeo]], [[1oes]], [[1oet]], [[1oeu]], [[1oev]], [[1sug]], [[2cm2]], [[2cm3]], [[3eu0]], [[3i80]], [[3a5j, [[6ntp]], [[6xe8]], [[6xee]], [[7key]], [[7l0c]], [[7lfo]], [[7rin]] - hPTP-1b catalytic domain <br />
+
**[[1a5y]], [[2hnp]], [[2hnq]], [[1oem]], [[1oeo]], [[1oes]], [[1oet]], [[1oeu]], [[1oev]], [[1sug]], [[2cm2]], [[2cm3]], [[3eu0]], [[3i80]], [[3a5j]], [[6ntp]], [[6xe8]], [[6xee]], [[7key]], [[7l0c]], [[7lfo]], [[7rin]] - hPTP-1b catalytic domain <br />
**[[1gfy]], [[1i57]], [[1pa1]], [[2f6f]], [[3a5k]], [[3zv2]], [[3qkp]], [[6olq]], [[6olv]], [[6omy]], [[6pfw]], [[6pg0]], [[6pgt]], [[6pha]], [[6phs]], [[6cwv]], [[6cwu]], [[7fre]], [[7frs]], [[7frt]], [[7fru]], [[7gsc]], [[7gtw]], [[7gtx]], [[7gty]], [[7gtz]], [[7gu0]], [[7gu1]], [[7gu2]], [[7gu3]], [[7gu4]], [[7gu5]], [[7gu6]], [[7gu7]], [[7gu8]], [[7gu9]], [[7gua]], [[7gub]], [[7guc]], [[7ken]], [[7mkz]], [[7mn9]], [[7mnc]], [[7mou]], [[7mov]], [[7s4f]], [[8du7]], [[8exi]], [[8xoy]] - hPTP-1b catalytic domain (mutant)
**[[1gfy]], [[1i57]], [[1pa1]], [[2f6f]], [[3a5k]], [[3zv2]], [[3qkp]], [[6olq]], [[6olv]], [[6omy]], [[6pfw]], [[6pg0]], [[6pgt]], [[6pha]], [[6phs]], [[6cwv]], [[6cwu]], [[7fre]], [[7frs]], [[7frt]], [[7fru]], [[7gsc]], [[7gtw]], [[7gtx]], [[7gty]], [[7gtz]], [[7gu0]], [[7gu1]], [[7gu2]], [[7gu3]], [[7gu4]], [[7gu5]], [[7gu6]], [[7gu7]], [[7gu8]], [[7gu9]], [[7gua]], [[7gub]], [[7guc]], [[7ken]], [[7mkz]], [[7mn9]], [[7mnc]], [[7mou]], [[7mov]], [[7s4f]], [[8du7]], [[8exi]], [[8xoy]] - hPTP-1b catalytic domain (mutant)
**[[3lnx]] - hPTP-1e PDZ2 domain 1361-1456<br />
**[[3lnx]] - hPTP-1e PDZ2 domain 1361-1456<br />
Line 52: Line 52:
**[[6gbd]] – mPTP-13 SH3 domain - NMR<br />
**[[6gbd]] – mPTP-13 SH3 domain - NMR<br />
**[[2pi7]] – cPTP CRYP-2 catalytic domain – chicken<br />
**[[2pi7]] – cPTP CRYP-2 catalytic domain – chicken<br />
-
**[[7mod]], [[7moi]], [[7moj]], [[7mok]], [[7mol]], [[7mom]] – AtPTP DSP1 49-215 – Arabidopsis thaliana <br />
+
**[[7mod]], [[7moi]], [[7moj]], [[7mok]], [[7mol]], [[7mom]] – AtPTP DSP1 49-215 – ''Arabidopsis thaliana'' <br />
**[[6krw]], [[6krx]] – AtPTP1 1-340 <br />
**[[6krw]], [[6krx]] – AtPTP1 1-340 <br />
**[[1d1p]], [[2j16]] – yPTP – yeast<br />
**[[1d1p]], [[2j16]] – yPTP – yeast<br />
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**[[5xw4]] – yPTPN CDC14 <br />
**[[5xw4]] – yPTPN CDC14 <br />
**[[6e3b]] – yPTPN SIW14 catalytic domain <br />
**[[6e3b]] – yPTPN SIW14 catalytic domain <br />
-
**[[1g4w]] – StPTP – Salmonella typhimurium<br />
+
**[[1g4w]] – StPTP – ''Salmonella typhimurium''<br />
-
**[[2i6i]], [[3ro1]] – SsPTP – Sulfolobus solfataricus<br />
+
**[[2i6i]], [[3ro1]] – SsPTP – ''Sulfolobus solfataricus''<br />
-
**[[2z72]], [[1v73]], [[2zbm]] – PTP residues 22-361 – Shewanella<br />
+
**[[2z72]], [[1v73]], [[2zbm]] – PTP residues 22-361 – ''Shewanella''<br />
-
**[[3js5]], [[3jvi]] – EhPTP – Entamoeba histolytica<br />
+
**[[3js5]], [[3jvi]] – EhPTP – ''Entamoeba histolytica''<br />
-
**[[2wjd]], [[2wje]], [[2wjf]] – PTP – Streptococcus pneumonia<br />
+
**[[2wjd]], [[2wje]], [[2wjf]] – PTP – ''Streptococcus pneumonia''<br />
-
**[[3qy6]], [[3qy7]], [[3qy8]] – BsPTP – Bacillus subtilis <br />
+
**[[3qy6]], [[3qy7]], [[3qy8]] – BsPTP – ''Bacillus subtilis'' <br />
-
**[[4d74]] – PTP AMSI 1-144 (mutant) – Erwinia amylovora <br />
+
**[[4d74]] – PTP AMSI 1-144 (mutant) – ''Erwinia amylovora'' <br />
-
**[[8dhi]], [[8dhj]] – PTP 1-246 (mutant) – Clostridioides difficile <br />
+
**[[8dhi]], [[8dhj]] – PTP 1-246 (mutant) – ''Clostridioides difficile'' <br />
*Non-receptor type PTP complex with peptide
*Non-receptor type PTP complex with peptide
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**[[2i6m]] – SsPTP + WO4<br />
**[[2i6m]] – SsPTP + WO4<br />
**[[3ido]] – EhPTP + HEPES<br />
**[[3ido]] – EhPTP + HEPES<br />
-
**[[7mpd]] – SsoPTP + inhibitor – Ssccharolobus solfataricus<br />
+
**[[7mpd]] – SsoPTP + inhibitor – ''Ssccharolobus solfataricus''<br />
**[[7mpc]] – SsoPTP + VO4<br />
**[[7mpc]] – SsoPTP + VO4<br />
-
**[[7ezn]] – PTP + VO4 – Cryptococcus neoformans<br />
+
**[[7ezn]] – PTP + VO4 – ''Cryptococcus neoformans''<br />
*Non-receptor type PTP complex with protein
*Non-receptor type PTP complex with protein
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**[[4dgp]] – hPTP SHP-2 SH2+catalytic domains 1-532<br />
**[[4dgp]] – hPTP SHP-2 SH2+catalytic domains 1-532<br />
-
**[[2shp]], [[4dgx]], [[4gwf]], [[4h1o]], [[4h34]], [[4nwf]], [[4nwg]], [[4ohd]], [[4ohe]], [[4ohh]], [[4ohi]], [[4ohl]], [[5bk8]], [[6ihz]], [[6crf]], [[6cmp]] – hPTP SHP-2 SH2+catalytic domains (mutant)<br />
+
**[[2shp]], [[4dgx]], [[4gwf]], [[4h1o]], [[4h34]], [[4nwf]], [[4nwg]], [[4ohd]], [[4ohe]], [[4ohh]], [[4ohi]], [[4ohl]], [[5bk8]], [[6crf]], [[6cmp]] – hPTP SHP-2 SH2+catalytic domains (mutant)<br />
**[[6cmq]] - hPTP SHP-2 106-529<br />
**[[6cmq]] - hPTP SHP-2 106-529<br />
**[[3b7o]], [[3zm0]], [[3zm1]], [[3zm2]], [[3zm3]] – hPTP SHP-2 catalytic domain 248-527<br />
**[[3b7o]], [[3zm0]], [[3zm1]], [[3zm2]], [[3zm3]] – hPTP SHP-2 catalytic domain 248-527<br />
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*Yersinia PTP Yop
*Yersinia PTP Yop
-
**[[1yts]], [[4yaa]], [[4z6b]], [[4zi4]], [[4zn5]], [[6xft]] - YePTP catalytic domain (mutant) – Yersinia enterocolitica<br />
+
**[[1yts]], [[4yaa]], [[4z6b]], [[4zi4]], [[4zn5]], [[6xft]] - YePTP catalytic domain (mutant) – ''Yersinia enterocolitica''<br />
**[[7l0i]] – YePTP (mutant) <br />
**[[7l0i]] – YePTP (mutant) <br />
**[[1xxp]], [[1xxv]] - YePTP catalytic domain (mutant) + peptide<br />
**[[1xxp]], [[1xxv]] - YePTP catalytic domain (mutant) + peptide<br />
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**[[1pa9]], [[3bm8]] - YePTP catalytic domain (mutant) + inhibitor<br />
**[[1pa9]], [[3bm8]] - YePTP catalytic domain (mutant) + inhibitor<br />
**[[3u96]] - YePTP catalytic domain (mutant) + PNCS<br />
**[[3u96]] - YePTP catalytic domain (mutant) + PNCS<br />
-
**[[1huf]] – YpPTP - Yersinia pestis<br />
+
**[[1huf]] – YpPTP - ''Yersinia pestis"<br />
**[[1qz0]] - YpPTP catalytic domain + peptide<br />
**[[1qz0]] - YpPTP catalytic domain + peptide<br />
**[[2y2f]] - YpPTP catalytic domain + inhibitor<br />
**[[2y2f]] - YpPTP catalytic domain + inhibitor<br />
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*Dual-specificity PTP DUSP see [[MAP kinase phosphatase]]
*Dual-specificity PTP DUSP see [[MAP kinase phosphatase]]
- 
*Class II – Low molecular weight PTP (LMW-PTP)
*Class II – Low molecular weight PTP (LMW-PTP)
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**[[5jnu]] – mLMW-PTP <br />
**[[5jnu]] – mLMW-PTP <br />
**[[7cuy]] – DmLMW-PTP <br />
**[[7cuy]] – DmLMW-PTP <br />
-
**[[1p8a]] – LMW-PTP (mutant) – Tritrichomonas foetus – NMR<br />
+
**[[1p8a]] – LMW-PTP (mutant) – ''Tritrichomonas foetus'' – NMR<br />
-
**[[2cwd]] – LMW-PTP – Thermus thermophilus<br />
+
**[[2cwd]] – LMW-PTP – ''Thermus thermophilus''<br />
-
**[[5got]] – LMW-PTP – Streptococcus pyogenes<br />
+
**[[5got]] – LMW-PTP – ''Streptococcus pyogenes''<br />
-
**[[1u2p]], [[2luo]] – MtLMW-PTP – Mycobacterium tuberculosis<br />
+
**[[1u2p]], [[2luo]] – MtLMW-PTP – ''Mycobacterium tuberculosis''<br />
-
**[[2fek]], [[2wja]] – LMW-PTP Wzb – Escherichia coli<br />
+
**[[2fek]], [[2wja]] – LMW-PTP Wzb – ''Escherichia coli''<br />
**[[4eti]], [[4etm]], [[4kk3]] – BsLMW-PTP<br />
**[[4eti]], [[4etm]], [[4kk3]] – BsLMW-PTP<br />
**[[4etn]], [[4kk4]] – BsLMW-PTP (mutant)<br />
**[[4etn]], [[4kk4]] – BsLMW-PTP (mutant)<br />
-
**[[7dhd]] – VvLMW-PTP Wzb – Vibrio vulnificus <br />
+
**[[7dhd]] – VvLMW-PTP Wzb – ''Vibrio vulnificus'' <br />
-
**[[4egs]] – LMW-PTP N-terminal 1-146 – Thermoanaerobacter tengcongensis <br />
+
**[[4egs]] – LMW-PTP N-terminal 1-146 – ''Thermoanaerobacter tengcongensis'' <br />
-
**[[2gi4]] – LMW-PTP – Campylobacter jejuni<br />
+
**[[2gi4]] – LMW-PTP – ''Campylobacter jejuni''<br />
*LMW-PTP complex
*LMW-PTP complex

Current revision

3D Structures of tyrosine phosphatase

Updated on 01-March-2024 - For a general description of the protein see Tyrosine phosphatase

3zmp, 3zmq, 4zrt – hPTPN1 catalytic domain + peptide

Proteopedia Page Contributors and Editors (what is this?)

Michal Harel, Joel L. Sussman

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