8j90
From Proteopedia
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- | '''Unreleased structure''' | ||
- | + | ==Cryo-EM structure of DDM1-nucleosome complex== | |
- | + | <StructureSection load='8j90' size='340' side='right'caption='[[8j90]], [[Resolution|resolution]] 4.71Å' scene=''> | |
- | + | == Structural highlights == | |
- | + | <table><tr><td colspan='2'>[[8j90]] is a 11 chain structure with sequence from [https://en.wikipedia.org/wiki/Arabidopsis_thaliana Arabidopsis thaliana] and [https://en.wikipedia.org/wiki/Synthetic_construct Synthetic construct]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=8J90 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=8J90 FirstGlance]. <br> | |
- | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Electron Microscopy, [[Resolution|Resolution]] 4.71Å</td></tr> | |
- | [[Category: | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=8j90 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=8j90 OCA], [https://pdbe.org/8j90 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=8j90 RCSB], [https://www.ebi.ac.uk/pdbsum/8j90 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=8j90 ProSAT]</span></td></tr> |
+ | </table> | ||
+ | == Function == | ||
+ | [https://www.uniprot.org/uniprot/H2A7_ARATH H2A7_ARATH] Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. | ||
+ | __TOC__ | ||
+ | </StructureSection> | ||
+ | [[Category: Arabidopsis thaliana]] | ||
+ | [[Category: Large Structures]] | ||
+ | [[Category: Synthetic construct]] | ||
+ | [[Category: Berger F]] | ||
+ | [[Category: Hatazawa S]] | ||
+ | [[Category: Horikoshi N]] | ||
+ | [[Category: Kakutani T]] | ||
+ | [[Category: Kurumizaka H]] | ||
+ | [[Category: Osakabe A]] | ||
+ | [[Category: Takizawa Y]] |
Current revision
Cryo-EM structure of DDM1-nucleosome complex
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