8s7x

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'''Unreleased structure'''
 
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The entry 8s7x is ON HOLD
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==Methyl-coenzyme M reductase activation complex without the A2 component==
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<StructureSection load='8s7x' size='340' side='right'caption='[[8s7x]], [[Resolution|resolution]] 2.78&Aring;' scene=''>
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Authors: Ramirez-Amador, F., Paul, S., Kumar, A., Schuller, J.M.
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== Structural highlights ==
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<table><tr><td colspan='2'>[[8s7x]] is a 11 chain structure with sequence from [https://en.wikipedia.org/wiki/Methanococcus_maripaludis Methanococcus maripaludis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=8S7X OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=8S7X FirstGlance]. <br>
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Description: Methyl-coenzyme M reductase activation complex without the A2 component
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Electron Microscopy, [[Resolution|Resolution]] 2.78&#8491;</td></tr>
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[[Category: Unreleased Structures]]
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=AGM:5-METHYL-ARGININE'>AGM</scene>, <scene name='pdbligand=COM:1-THIOETHANESULFONIC+ACID'>COM</scene>, <scene name='pdbligand=GL3:THIOGLYCIN'>GL3</scene>, <scene name='pdbligand=MGN:2-METHYL-GLUTAMINE'>MGN</scene>, <scene name='pdbligand=MHS:N1-METHYLATED+HISTIDINE'>MHS</scene>, <scene name='pdbligand=SHT:O-PHOSPHONO-N-{(2E)-7-[(2-SULFOETHYL)DITHIO]HEPT-2-ENOYL}-L-THREONINE'>SHT</scene>, <scene name='pdbligand=SMC:S-METHYLCYSTEINE'>SMC</scene>, <scene name='pdbligand=TP7:COENZYME+B'>TP7</scene></td></tr>
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[[Category: Kumar, A]]
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=8s7x FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=8s7x OCA], [https://pdbe.org/8s7x PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=8s7x RCSB], [https://www.ebi.ac.uk/pdbsum/8s7x PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=8s7x ProSAT]</span></td></tr>
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[[Category: Paul, S]]
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</table>
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[[Category: Ramirez-Amador, F]]
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== Function ==
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[[Category: Schuller, J.M]]
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[https://www.uniprot.org/uniprot/A0A2L1CBG2_METMI A0A2L1CBG2_METMI] Component of the methyl-coenzyme M reductase (MCR) I that catalyzes the reductive cleavage of methyl-coenzyme M (CoM-S-CH3 or 2-(methylthio)ethanesulfonate) using coenzyme B (CoB or 7-mercaptoheptanoylthreonine phosphate) as reductant which results in the production of methane and the mixed heterodisulfide of CoB and CoM (CoM-S-S-CoB). This is the final step in methanogenesis.[ARBA:ARBA00002461]
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__TOC__
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</StructureSection>
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[[Category: Large Structures]]
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[[Category: Methanococcus maripaludis]]
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[[Category: Kumar A]]
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[[Category: Paul S]]
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[[Category: Ramirez-Amador F]]
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[[Category: Schuller JM]]

Current revision

Methyl-coenzyme M reductase activation complex without the A2 component

PDB ID 8s7x

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