Cefixime
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Cefixime, sold under the brand name Suprax among others, is an antibiotic medication used to treat a number of bacterial infections. These infections include otitis media, strep throat, pneumonia, urinary tract infections, gonorrhea, and Lyme disease.<ref name="a3">[https://www.drugs.com/monograph/cefixime.html "Cefixime".] The American Society of Health—System Pharmacists. Archived from the original on 27 November 2016. Retrieved 8 December 2016.</ref> The bactericidal action of Cefixime is due to the inhibition of cell wall synthesis. It binds to one of the penicillin binding proteins (PBPs) which inhibits the final transpeptidation step of the peptidoglycan synthesis in the bacterial cell wall, thus inhibiting biosynthesis and arresting cell wall assembly resulting in bacterial cell death. See also [https://en.wikipedia.org/wiki/Cefixime Cefixime]. | Cefixime, sold under the brand name Suprax among others, is an antibiotic medication used to treat a number of bacterial infections. These infections include otitis media, strep throat, pneumonia, urinary tract infections, gonorrhea, and Lyme disease.<ref name="a3">[https://www.drugs.com/monograph/cefixime.html "Cefixime".] The American Society of Health—System Pharmacists. Archived from the original on 27 November 2016. Retrieved 8 December 2016.</ref> The bactericidal action of Cefixime is due to the inhibition of cell wall synthesis. It binds to one of the penicillin binding proteins (PBPs) which inhibits the final transpeptidation step of the peptidoglycan synthesis in the bacterial cell wall, thus inhibiting biosynthesis and arresting cell wall assembly resulting in bacterial cell death. See also [https://en.wikipedia.org/wiki/Cefixime Cefixime]. | ||
- | [[6p55]]. | + | <scene name='10/1033693/Cv/2'>Crystal structure of transpeptidase domain of PBP2 from Neisseria gonorrhoeae acylated by cefixime</scene> ([[6p55]]). |
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+ | <scene name='10/1033693/Cv/3'>Cefixime binding site</scene>. | ||
See also: | See also: |
Current revision
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References
- ↑ "Cefixime". The American Society of Health—System Pharmacists. Archived from the original on 27 November 2016. Retrieved 8 December 2016.