User:Sam Reichenbach/Sandbox 1
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=H. Sapiens GLP-1 Hormone Bound to GLP-1 Receptor= | =H. Sapiens GLP-1 Hormone Bound to GLP-1 Receptor= | ||
| - | <StructureSection load='6x18' size=' | + | <StructureSection load='6x18' size='350' frame='true' side='right' caption='GLP-1 6x18' scene='View_of_ligand'> |
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| - | + | ==Introduction== | |
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| + | Welcome to the one-stop spot for all things GLP-1 related. GLP-1, or Glucagon-Like Peptide-1, is a hormone produced in the gut that stimulates insulin release, inhibits glucagon secretion, and slows gastric emptying, helping regulate blood sugar levels. It's a key player in diabetes management and is targeted by medications to improve blood sugar control. | ||
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| + | Browse this draft of a protopedia page. Some scenes need to be edited and others are still in construction, but they will be added next Tuesday 4/16. | ||
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| + | Enjoy! | ||
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| + | [[Image:6x18.png|400px|left|thumb|Figure 1. The coolest image of this protein EVAH!!]] | ||
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| + | [https://en.wikipedia.org/wiki/Glucagon-like_peptide-1 Wikipedia Page on GLP-1] | ||
== Function == | == Function == | ||
| - | == | + | ==Mechanism== |
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| + | <scene name='10/1037521/Glp-1_cleavage_site/1'>GLP-1 Cleavage Site</scene> | ||
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| + | <scene name='10/1037521/Clipptirz/2'>Crucial Modifications of Tirzepatide</scene> | ||
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== Relevance == | == Relevance == | ||
| + | <scene name='10/1037521/Apo_form/1'>Apo Form</scene> | ||
== Structural highlights == | == Structural highlights == | ||
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| + | ===Active Site=== | ||
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| + | <<scene name='10/1037521/Glp-1_n-term_h-q/1'>GLP-1 N-Terminus</scene> | ||
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| + | ===Extracellular Domain=== | ||
This is a sample scene created with SAT to <scene name="/12/3456/Sample/1">color</scene> by Group, and another to make <scene name="/12/3456/Sample/2">a transparent representation</scene> of the protein. You can make your own scenes on SAT starting from scratch or loading and editing one of these sample scenes. | This is a sample scene created with SAT to <scene name="/12/3456/Sample/1">color</scene> by Group, and another to make <scene name="/12/3456/Sample/2">a transparent representation</scene> of the protein. You can make your own scenes on SAT starting from scratch or loading and editing one of these sample scenes. | ||
</StructureSection> | </StructureSection> | ||
| - | == References == | + | ==References== |
| + | <ref name="Ransey">PMID:28504306</ref> | ||
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<references/> | <references/> | ||
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| + | ==Student Contributors== | ||
| + | *Sam Reichenbach | ||
| + | *Preston Roa | ||
| + | *Jack Guckien | ||
Current revision
H. Sapiens GLP-1 Hormone Bound to GLP-1 Receptor
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References
- ↑ Ransey E, Paredes E, Dey SK, Das SR, Heroux A, Macbeth MR. Crystal structure of the Entamoeba histolytica RNA lariat debranching enzyme EhDbr1 reveals a catalytic Zn(2+) /Mn(2+) heterobinucleation. FEBS Lett. 2017 Jul;591(13):2003-2010. doi: 10.1002/1873-3468.12677. Epub 2017, Jun 14. PMID:28504306 doi:http://dx.doi.org/10.1002/1873-3468.12677
Student Contributors
- Sam Reichenbach
- Preston Roa
- Jack Guckien
