User:Jack Guckien/Sandbox1
From Proteopedia
< User:Jack Guckien(Difference between revisions)
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| - | <StructureSection load='7rg9' size='350' frame='true' side='right' caption='GLP-1 Receptor, | + | <StructureSection load='7rg9' size='350' frame='true' side='right' caption='Tirzepatide bound to GLP-1 Receptor, 7RGP' scene='10/1037513/7rgp_-_tirzepatide_bound/1'> |
== Introduction == | == Introduction == | ||
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===Active Site=== | ===Active Site=== | ||
| + | <scene name='10/1037513/7rgp_-_tirzepatide_boundcartoo/1'>Tirzepatide Bound Overview Cartoon</scene> | ||
| + | <scene name='10/1037513/7rgp_-_tirzepatide_boundsticks/1'>Tirzepatide Bound Overview Sticks</scene> | ||
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| + | <scene name='10/1037513/7rgp-_2aib_mutation/3'>Tirzepatide 2AIB Mutation</scene> | ||
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| + | <scene name='10/1037513/7rgp_-_13aib_mutation/3'>Tirzepatide 13AIB Mutation</scene> | ||
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| + | <scene name='10/1037513/Y1_hbond_w_q234/7'>Tirz Hbond Y1 Q234</scene> | ||
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| + | <scene name='10/1037513/Pi_stacking_y10_and_y145/4'>Pi Stacking Y10 (Tirzepatide) and Y145 (GLP-1R)</scene> | ||
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| + | <scene name='10/1037513/Glp_bound_to_glp-1r_h_bonds/3'>GLP-1 bound to GLP-1R H-bonds</scene> | ||
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| + | <scene name='10/1037513/Glp_bound_to_glp-1r_no_clash/2'>GLP-1 bound to GLP-1R: interactions, no steric clash</scene> | ||
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| + | <scene name='10/1037513/Tirz_intxn_glp-1r_steric_clash/2'>Tirzepatide bound to GLP-1R: steric clashing </scene> | ||
==Drug Applications== | ==Drug Applications== | ||
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== References == | == References == | ||
<references/> | <references/> | ||
| + | <ref name="Wan">PMID:36677809</ref> | ||
Current revision
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