This old version of Proteopedia is provided for student assignments while the new version is undergoing repairs. Content and edits done in this old version of Proteopedia after March 1, 2026 will eventually be lost when it is retired in about June of 2026.
Apply for new accounts at the new Proteopedia. Your logins will work in both the old and new versions.
User:Sam Reichenbach/Sandbox 1
From Proteopedia
< User:Sam Reichenbach(Difference between revisions)
m |
|||
| (10 intermediate revisions not shown.) | |||
| Line 3: | Line 3: | ||
==Introduction== | ==Introduction== | ||
| - | + | ||
| - | + | Welcome to the one-stop spot for all things GLP-1 related. GLP-1, or Glucagon-Like Peptide-1, is a hormone produced in the gut that stimulates insulin release, inhibits glucagon secretion, and slows gastric emptying, helping regulate blood sugar levels. It's a key player in diabetes management and is targeted by medications to improve blood sugar control. | |
| + | |||
| + | Browse this draft of a protopedia page. Some scenes need to be edited and others are still in construction, but they will be added next Tuesday 4/16. | ||
| + | |||
| + | Enjoy! | ||
| + | |||
[[Image:6x18.png|400px|left|thumb|Figure 1. The coolest image of this protein EVAH!!]] | [[Image:6x18.png|400px|left|thumb|Figure 1. The coolest image of this protein EVAH!!]] | ||
| Line 13: | Line 18: | ||
==Mechanism== | ==Mechanism== | ||
| + | |||
| + | <scene name='10/1037521/Glp-1_cleavage_site/1'>GLP-1 Cleavage Site</scene> | ||
| + | |||
| + | <scene name='10/1037521/Clipptirz/2'>Crucial Modifications of Tirzepatide</scene> | ||
| + | |||
== Relevance == | == Relevance == | ||
| + | <scene name='10/1037521/Apo_form/1'>Apo Form</scene> | ||
== Structural highlights == | == Structural highlights == | ||
| + | |||
| + | |||
===Active Site=== | ===Active Site=== | ||
| - | <scene name='10/1037521/ | + | |
| + | <<scene name='10/1037521/Glp-1_n-term_h-q/1'>GLP-1 N-Terminus</scene> | ||
===Extracellular Domain=== | ===Extracellular Domain=== | ||
| Line 27: | Line 41: | ||
</StructureSection> | </StructureSection> | ||
==References== | ==References== | ||
| + | <ref name="Ransey">PMID:28504306</ref> | ||
| + | |||
<references/> | <references/> | ||
| - | <ref name="Ransey"/> | ||
==Student Contributors== | ==Student Contributors== | ||
Current revision
H. Sapiens GLP-1 Hormone Bound to GLP-1 Receptor
| |||||||||||
References
- ↑ Ransey E, Paredes E, Dey SK, Das SR, Heroux A, Macbeth MR. Crystal structure of the Entamoeba histolytica RNA lariat debranching enzyme EhDbr1 reveals a catalytic Zn(2+) /Mn(2+) heterobinucleation. FEBS Lett. 2017 Jul;591(13):2003-2010. doi: 10.1002/1873-3468.12677. Epub 2017, Jun 14. PMID:28504306 doi:http://dx.doi.org/10.1002/1873-3468.12677
Student Contributors
- Sam Reichenbach
- Preston Roa
- Jack Guckien
