1tmw

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(New page: 200px<br /> <applet load="1tmw" size="450" color="white" frame="true" align="right" spinBox="true" caption="1tmw" /> '''Solution structure of Human Coactosin Like ...)
Current revision (08:42, 1 May 2024) (edit) (undo)
 
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[[Image:1tmw.gif|left|200px]]<br />
 
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<applet load="1tmw" size="450" color="white" frame="true" align="right" spinBox="true"
 
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caption="1tmw" />
 
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'''Solution structure of Human Coactosin Like Protein D123N'''<br />
 
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==Disease==
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==Solution structure of Human Coactosin Like Protein D123N==
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Known disease associated with this structure: Cardiomyopathy, dilated, 1M OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=600824 600824]]
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<StructureSection load='1tmw' size='340' side='right'caption='[[1tmw]]' scene=''>
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== Structural highlights ==
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==About this Structure==
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<table><tr><td colspan='2'>[[1tmw]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1TMW OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1TMW FirstGlance]. <br>
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1TMW is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://ispc.weizmann.ac.il/oca-bin/ocashort?id=1TMW OCA].
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Solution NMR</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1tmw FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1tmw OCA], [https://pdbe.org/1tmw PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1tmw RCSB], [https://www.ebi.ac.uk/pdbsum/1tmw PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1tmw ProSAT]</span></td></tr>
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</table>
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== Function ==
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[https://www.uniprot.org/uniprot/COTL1_HUMAN COTL1_HUMAN] Binds to F-actin in a calcium-independent manner. Has no direct effect on actin depolymerization.<ref>PMID:11583571</ref>
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== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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Check<jmol>
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<jmolCheckbox>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/tm/1tmw_consurf.spt"</scriptWhenChecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<text>to colour the structure by Evolutionary Conservation</text>
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</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1tmw ConSurf].
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<div style="clear:both"></div>
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== References ==
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<references/>
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__TOC__
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</StructureSection>
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
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[[Category: Single protein]]
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[[Category: Large Structures]]
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[[Category: Dai, H.]]
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[[Category: Dai H]]
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[[Category: Ding, H.]]
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[[Category: Ding H]]
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[[Category: Shi, Y.]]
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[[Category: Shi Y]]
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[[Category: Tang, Y.]]
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[[Category: Tang Y]]
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[[Category: Wu, J.]]
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[[Category: Wu J]]
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[[Category: Xu, Y.]]
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[[Category: Xu Y]]
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[[Category: coactosin-like protein]]
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''Page seeded by [http://ispc.weizmann.ac.il/oca OCA ] on Mon Nov 12 19:26:03 2007''
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Current revision

Solution structure of Human Coactosin Like Protein D123N

PDB ID 1tmw

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Proteopedia Page Contributors and Editors (what is this?)

OCA

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