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User:Michela Jordan/Sandbox1
From Proteopedia
< User:Michela Jordan(Difference between revisions)
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==''Glucagon-Like Peptide 1 Receptor (GLP-1R)''== | ==''Glucagon-Like Peptide 1 Receptor (GLP-1R)''== | ||
| - | <StructureSection load='6x18' size='340' side='right' caption='Caption for this structure' scene=''> | + | <StructureSection load='6x18' size='340' side='right' caption='Caption for this structure' scene='10/1038821/Receptor/1'> |
| - | + | ||
You may include any references to papers as in: the use of JSmol in Proteopedia <ref>DOI 10.1002/ijch.201300024</ref> or to the article describing Jmol <ref>PMID:21638687</ref> to the rescue. | You may include any references to papers as in: the use of JSmol in Proteopedia <ref>DOI 10.1002/ijch.201300024</ref> or to the article describing Jmol <ref>PMID:21638687</ref> to the rescue. | ||
== Function == | == Function == | ||
| + | [[Image:hormone_wholeimage.png|400 px|right|thumb|figure 1]] | ||
== Disease == | == Disease == | ||
=== Diabetes and Obesity === | === Diabetes and Obesity === | ||
| + | [https://www.cdc.gov/obesity/index.html obesity facts] | ||
| + | |||
| + | == Ligand and Receptor Interactions == | ||
| + | === Hormone Interaction === | ||
| + | === Drug Interactions === | ||
| + | <scene name='10/1038822/Trizep_receptor_trp/9'>Interaction between Tirzepetide and Receptor with pi stacking</scene> | ||
| + | |||
| + | <scene name='10/1038822/Trizep_receptor_interaction_2/11'>Tirzepatide and Receptor interactions at the N-term of Tirzepatide</scene> | ||
| + | |||
== Relevance == | == Relevance == | ||
| + | <ref name="Ransey">PMID:28504306</ref>. | ||
| + | <ref name="Meier">PMID:22945360</ref>. | ||
== Structural highlights == | == Structural highlights == | ||
| + | |||
This is a sample scene created with SAT to <scene name="/12/3456/Sample/1">color</scene> by Group, and another to make <scene name="/12/3456/Sample/2">a transparent representation</scene> of the protein. You can make your own scenes on SAT starting from scratch or loading and editing one of these sample scenes. | This is a sample scene created with SAT to <scene name="/12/3456/Sample/1">color</scene> by Group, and another to make <scene name="/12/3456/Sample/2">a transparent representation</scene> of the protein. You can make your own scenes on SAT starting from scratch or loading and editing one of these sample scenes. | ||
Current revision
Glucagon-Like Peptide 1 Receptor (GLP-1R)
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References
- ↑ Hanson, R. M., Prilusky, J., Renjian, Z., Nakane, T. and Sussman, J. L. (2013), JSmol and the Next-Generation Web-Based Representation of 3D Molecular Structure as Applied to Proteopedia. Isr. J. Chem., 53:207-216. doi:http://dx.doi.org/10.1002/ijch.201300024
- ↑ Herraez A. Biomolecules in the computer: Jmol to the rescue. Biochem Mol Biol Educ. 2006 Jul;34(4):255-61. doi: 10.1002/bmb.2006.494034042644. PMID:21638687 doi:10.1002/bmb.2006.494034042644
- ↑ Ransey E, Paredes E, Dey SK, Das SR, Heroux A, Macbeth MR. Crystal structure of the Entamoeba histolytica RNA lariat debranching enzyme EhDbr1 reveals a catalytic Zn(2+) /Mn(2+) heterobinucleation. FEBS Lett. 2017 Jul;591(13):2003-2010. doi: 10.1002/1873-3468.12677. Epub 2017, Jun 14. PMID:28504306 doi:http://dx.doi.org/10.1002/1873-3468.12677
- ↑ Meier JJ. GLP-1 receptor agonists for individualized treatment of type 2 diabetes mellitus. Nat Rev Endocrinol. 2012 Dec;8(12):728-42. PMID:22945360 doi:10.1038/nrendo.2012.140
