8ype
From Proteopedia
(Difference between revisions)
(New page: '''Unreleased structure''' The entry 8ype is ON HOLD Authors: Zhang, Y.Y., Pei, C.J., He, Q.Q., Luo, Z.P., Wu, J.W., Wang, Z.X. Description: The crystal structure of inactive p38 compl...) |
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- | '''Unreleased structure''' | ||
- | The | + | ==The crystal structure of inactive p38 complexed with a ATF2 from 46 to 80== |
- | + | <StructureSection load='8ype' size='340' side='right'caption='[[8ype]], [[Resolution|resolution]] 1.95Å' scene=''> | |
- | + | == Structural highlights == | |
- | + | <table><tr><td colspan='2'>[[8ype]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens] and [https://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=8YPE OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=8YPE FirstGlance]. <br> | |
- | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.95Å</td></tr> | |
- | [[Category: | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=8ype FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=8ype OCA], [https://pdbe.org/8ype PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=8ype RCSB], [https://www.ebi.ac.uk/pdbsum/8ype PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=8ype ProSAT]</span></td></tr> |
- | [[Category: | + | </table> |
- | [[Category: | + | == Function == |
- | [[Category: | + | [https://www.uniprot.org/uniprot/ATF2_HUMAN ATF2_HUMAN] Transcriptional activator, probably constitutive, which binds to the cAMP-responsive element (CRE) (consensus: 5'-GTGACGT[AC][AG]-3'), a sequence present in many viral and cellular promoters. Interaction with JUN redirects JUN to bind to CRES preferentially over the 12-O-tetradecanoylphorbol-13-acetate response elements (TRES) as part of an ATF2/JUN complex. |
- | [[Category: | + | __TOC__ |
- | [[Category: | + | </StructureSection> |
- | [[Category: | + | [[Category: Homo sapiens]] |
+ | [[Category: Large Structures]] | ||
+ | [[Category: Mus musculus]] | ||
+ | [[Category: He QQ]] | ||
+ | [[Category: Luo ZP]] | ||
+ | [[Category: Pei CJ]] | ||
+ | [[Category: Wang ZX]] | ||
+ | [[Category: Wu JW]] | ||
+ | [[Category: Zhang YY]] |
Current revision
The crystal structure of inactive p38 complexed with a ATF2 from 46 to 80
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Categories: Homo sapiens | Large Structures | Mus musculus | He QQ | Luo ZP | Pei CJ | Wang ZX | Wu JW | Zhang YY