9b2f
From Proteopedia
(Difference between revisions)
(New page: '''Unreleased structure''' The entry 9b2f is ON HOLD until Paper Publication Authors: Pakhomova, S., Belyaeva, O.V., Boeglin, W.E., Kedishvili, N.Y., Brash, A.R., Newcomer, M.E., Popov,...) |
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| - | '''Unreleased structure''' | ||
| - | + | ==Crystal structure of short chain dehydrogenase reductase 9 (short chain dehydrogenase reductase 9C4) in complex with NAD+== | |
| - | + | <StructureSection load='9b2f' size='340' side='right'caption='[[9b2f]], [[Resolution|resolution]] 1.66Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[9b2f]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=9B2F OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=9B2F FirstGlance]. <br> | |
| - | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.662Å</td></tr> | |
| - | [[Category: | + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=MLI:MALONATE+ION'>MLI</scene>, <scene name='pdbligand=NAD:NICOTINAMIDE-ADENINE-DINUCLEOTIDE'>NAD</scene></td></tr> |
| - | [[Category: | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=9b2f FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=9b2f OCA], [https://pdbe.org/9b2f PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=9b2f RCSB], [https://www.ebi.ac.uk/pdbsum/9b2f PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=9b2f ProSAT]</span></td></tr> |
| - | [[Category: Belyaeva | + | </table> |
| - | [[Category: | + | == Function == |
| - | [[Category: | + | [https://www.uniprot.org/uniprot/DHRS9_MOUSE DHRS9_MOUSE] 3-alpha-hydroxysteroid dehydrogenase that converts 3-alpha-tetrahydroprogesterone (allopregnanolone) to dihydroxyprogesterone and 3-alpha-androstanediol to dihydroxyprogesterone. Also plays a role in the biosynthesis of retinoic acid. Can utilize both NADH and NADPH.[UniProtKB:Q8VD48][UniProtKB:Q9BPW9] |
| - | [[Category: | + | __TOC__ |
| - | [[Category: Newcomer | + | </StructureSection> |
| - | [[Category: | + | [[Category: Large Structures]] |
| + | [[Category: Mus musculus]] | ||
| + | [[Category: Belyaeva OV]] | ||
| + | [[Category: Boeglin WE]] | ||
| + | [[Category: Brash AR]] | ||
| + | [[Category: Kedishvili NY]] | ||
| + | [[Category: Newcomer ME]] | ||
| + | [[Category: Pakhomova S]] | ||
| + | [[Category: Popov KM]] | ||
Current revision
Crystal structure of short chain dehydrogenase reductase 9 (short chain dehydrogenase reductase 9C4) in complex with NAD+
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