9au8
From Proteopedia
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| - | '''Unreleased structure''' | ||
| - | + | ==Ternary complex of human DNA polymerase theta polymerase domain with a mismatched T:T base pair== | |
| - | + | <StructureSection load='9au8' size='340' side='right'caption='[[9au8]], [[Resolution|resolution]] 3.44Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[9au8]] is a 3 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=9AU8 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=9AU8 FirstGlance]. <br> | |
| - | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Electron Microscopy, [[Resolution|Resolution]] 3.44Å</td></tr> | |
| - | [[Category: | + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=DOC:2,3-DIDEOXYCYTIDINE-5-MONOPHOSPHATE'>DOC</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=TTP:THYMIDINE-5-TRIPHOSPHATE'>TTP</scene></td></tr> |
| - | [[Category: Gao | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=9au8 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=9au8 OCA], [https://pdbe.org/9au8 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=9au8 RCSB], [https://www.ebi.ac.uk/pdbsum/9au8 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=9au8 ProSAT]</span></td></tr> |
| - | [[Category: Li | + | </table> |
| + | == Function == | ||
| + | [https://www.uniprot.org/uniprot/DPOLQ_HUMAN DPOLQ_HUMAN] Has a DNA polymerase activity on nicked double-stranded DNA and on a singly primed DNA template. The enzyme activity is resistant to aphidicolin, and inhibited by dideoxynucleotides. Exhibites a single-stranded DNA-dependent ATPase activity. Could be involved in the repair of interstrand cross-links.<ref>PMID:14576298</ref> | ||
| + | == References == | ||
| + | <references/> | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
| + | [[Category: Homo sapiens]] | ||
| + | [[Category: Large Structures]] | ||
| + | [[Category: Gao Y]] | ||
| + | [[Category: Li C]] | ||
Current revision
Ternary complex of human DNA polymerase theta polymerase domain with a mismatched T:T base pair
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