9b2g
From Proteopedia
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| - | '''Unreleased structure''' | ||
| - | + | ==Crystal structure of short chain dehydrogenase reductase 9 (short chain dehydrogenase reductase 9C4) in complex with NADH== | |
| - | + | <StructureSection load='9b2g' size='340' side='right'caption='[[9b2g]], [[Resolution|resolution]] 2.00Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[9b2g]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=9B2G OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=9B2G FirstGlance]. <br> | |
| - | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2Å</td></tr> | |
| - | [[Category: | + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=NAI:1,4-DIHYDRONICOTINAMIDE+ADENINE+DINUCLEOTIDE'>NAI</scene></td></tr> |
| - | [[Category: | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=9b2g FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=9b2g OCA], [https://pdbe.org/9b2g PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=9b2g RCSB], [https://www.ebi.ac.uk/pdbsum/9b2g PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=9b2g ProSAT]</span></td></tr> |
| - | [[Category: Belyaeva | + | </table> |
| - | [[Category: | + | == Function == |
| - | [[Category: | + | [https://www.uniprot.org/uniprot/DHRS9_MOUSE DHRS9_MOUSE] 3-alpha-hydroxysteroid dehydrogenase that converts 3-alpha-tetrahydroprogesterone (allopregnanolone) to dihydroxyprogesterone and 3-alpha-androstanediol to dihydroxyprogesterone. Also plays a role in the biosynthesis of retinoic acid. Can utilize both NADH and NADPH.[UniProtKB:Q8VD48][UniProtKB:Q9BPW9] |
| - | [[Category: | + | __TOC__ |
| - | [[Category: Newcomer | + | </StructureSection> |
| - | [[Category: | + | [[Category: Large Structures]] |
| + | [[Category: Mus musculus]] | ||
| + | [[Category: Belyaeva OV]] | ||
| + | [[Category: Boeglin WE]] | ||
| + | [[Category: Brash AR]] | ||
| + | [[Category: Kedishvili NY]] | ||
| + | [[Category: Newcomer ME]] | ||
| + | [[Category: Pakhomova S]] | ||
| + | [[Category: Popov KM]] | ||
Current revision
Crystal structure of short chain dehydrogenase reductase 9 (short chain dehydrogenase reductase 9C4) in complex with NADH
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