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User:Emma Edwards/Sandbox 1

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<scene name='10/1037512/Residues_1-20_crazy/10'>Text To Be Displayed</scene><scene name='10/1037512/Residues_1-20_crazy/1'>Text To Be Displayed</scene>=''Glucose-Dependent Insulinotropic Polypeptide Receptor''=
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<StructureSection load='7ra3' size='350' side='true' caption='GIP Bound to GIP-R 7RA3' scene''>
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<StructureSection load='7ra3' size='350' side='true' caption='GIP Bound to GIP-R 7RA3' scene='10/1037512/Residues_1-20_crazy/1'>
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==Introduction==
==Introduction==
==Structure==
==Structure==
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<scene name='10/1037512/Gip_ecd_pi_stacking/7'>GIP Pi Stacking to GIPR in ECD</scene>
<scene name='10/1037512/Gip_ecd_pi_stacking/7'>GIP Pi Stacking to GIPR in ECD</scene>
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Edited: <scene name='10/1037512/Gip_ecd_pi_stacking/10'>GIP Pi stacking to GIP-R in ECD</scene>
<scene name='10/1037512/Tirz_gipr_ecd_pi_stacking/1'>Tirzepatide Pi Stacking to GIPR in ECD</scene>
<scene name='10/1037512/Tirz_gipr_ecd_pi_stacking/1'>Tirzepatide Pi Stacking to GIPR in ECD</scene>
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Edited: <scene name='10/1037512/Tirz_gipr_ecd_pi_stacking/2'>Tirzepatide bound to GIP-R in extracellular domain</scene>
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<scene name='10/1037512/Overview_gip_gip-r/1'>Overview: GIP in GIP-R</scene>
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Edited: <scene name='10/1037512/Overview_gip_gip-r/2'>GIP bound to GIP-R</scene>
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== Function ==
== Function ==
===Insulin Secretion===
===Insulin Secretion===

Current revision

GIP Bound to GIP-R 7RA3

Drag the structure with the mouse to rotate

References

[1] [2]

  1. ↑ Ransey E, Paredes E, Dey SK, Das SR, Heroux A, Macbeth MR. Crystal structure of the Entamoeba histolytica RNA lariat debranching enzyme EhDbr1 reveals a catalytic Zn(2+) /Mn(2+) heterobinucleation. FEBS Lett. 2017 Jul;591(13):2003-2010. doi: 10.1002/1873-3468.12677. Epub 2017, Jun 14. PMID:28504306 doi:http://dx.doi.org/10.1002/1873-3468.12677
  2. ↑ Sun B, Willard FS, Feng D, Alsina-Fernandez J, Chen Q, Vieth M, Ho JD, Showalter AD, Stutsman C, Ding L, Suter TM, Dunbar JD, Carpenter JW, Mohammed FA, Aihara E, Brown RA, Bueno AB, Emmerson PJ, Moyers JS, Kobilka TS, Coghlan MP, Kobilka BK, Sloop KW. Structural determinants of dual incretin receptor agonism by tirzepatide. Proc Natl Acad Sci U S A. 2022 Mar 29;119(13):e2116506119. PMID:35333651 doi:10.1073/pnas.2116506119

Student Contributors

Emma Edwards

Proteopedia Page Contributors and Editors (what is this?)

Emma Edwards

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