7h6e
From Proteopedia
(Difference between revisions)
(New page: '''Unreleased structure''' The entry 7h6e is ON HOLD Authors: Banner, D.W., Benz, J.M., Schlatter, D., Hilpert, H. Description: THE 2.0 A CRYSTAL STRUCTURE OF HUMAN CHYMASE IN COMPLEX ...) |
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| - | '''Unreleased structure''' | ||
| - | + | ==THE 2.0 A CRYSTAL STRUCTURE OF HUMAN CHYMASE IN COMPLEX WITH 5-fluoro-3-methyl-N-(2-methylsulfonyl-4-pyridin-4-ylphenyl)-1-benzothiophene-2-sulfonamide== | |
| - | + | <StructureSection load='7h6e' size='340' side='right'caption='[[7h6e]], [[Resolution|resolution]] 2.00Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[7h6e]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7H6E OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7H6E FirstGlance]. <br> | |
| - | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2Å</td></tr> | |
| - | [[ | + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=A1AOP:5-fluoranyl-3-methyl-~{N}-(2-methylsulfonyl-4-pyridin-4-yl-phenyl)-1-benzothiophene-2-sulfonamide'>A1AOP</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr> |
| - | [[ | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7h6e FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7h6e OCA], [https://pdbe.org/7h6e PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7h6e RCSB], [https://www.ebi.ac.uk/pdbsum/7h6e PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7h6e ProSAT]</span></td></tr> |
| - | [[ | + | </table> |
| - | [[Category: Banner | + | == Function == |
| - | [[Category: Benz | + | [https://www.uniprot.org/uniprot/CMA1_HUMAN CMA1_HUMAN] Major secreted protease of mast cells with suspected roles in vasoactive peptide generation, extracellular matrix degradation, and regulation of gland secretion. |
| + | __TOC__ | ||
| + | </StructureSection> | ||
| + | [[Category: Homo sapiens]] | ||
| + | [[Category: Large Structures]] | ||
| + | [[Category: Banner DW]] | ||
| + | [[Category: Benz JM]] | ||
| + | [[Category: Hilpert H]] | ||
| + | [[Category: Schlatter D]] | ||
Current revision
THE 2.0 A CRYSTAL STRUCTURE OF HUMAN CHYMASE IN COMPLEX WITH 5-fluoro-3-methyl-N-(2-methylsulfonyl-4-pyridin-4-ylphenyl)-1-benzothiophene-2-sulfonamide
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