8khr
From Proteopedia
(Difference between revisions)
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| - | '''Unreleased structure''' | ||
| - | + | ==Cryo-EM structure of EBV gH/gL-gp42 in complex with fab 2C1== | |
| - | + | <StructureSection load='8khr' size='340' side='right'caption='[[8khr]], [[Resolution|resolution]] 3.25Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[8khr]] is a 5 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens] and [https://en.wikipedia.org/wiki/Human_gammaherpesvirus_4 Human gammaherpesvirus 4]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=8KHR OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=8KHR FirstGlance]. <br> | |
| - | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Electron Microscopy, [[Resolution|Resolution]] 3.25Å</td></tr> | |
| - | [[Category: | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=8khr FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=8khr OCA], [https://pdbe.org/8khr PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=8khr RCSB], [https://www.ebi.ac.uk/pdbsum/8khr PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=8khr ProSAT]</span></td></tr> |
| + | </table> | ||
| + | == Function == | ||
| + | [https://www.uniprot.org/uniprot/GP42_EBVG GP42_EBVG] Plays a role in virion attachment to host B-lymphocytes, through binding to leukocyte antigen (HLA) class II and subsequently participates in fusion of the virion with host membranes. May act as a tropism switch that directs fusion with B-lymphocytes and inhibits fusion with epithelial cells (By similarity). | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
| + | [[Category: Homo sapiens]] | ||
| + | [[Category: Human gammaherpesvirus 4]] | ||
| + | [[Category: Large Structures]] | ||
| + | [[Category: Fang XY]] | ||
| + | [[Category: Liu Z]] | ||
| + | [[Category: Zeng MS]] | ||
| + | [[Category: Zhao GX]] | ||
Current revision
Cryo-EM structure of EBV gH/gL-gp42 in complex with fab 2C1
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