8z50

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(New page: '''Unreleased structure''' The entry 8z50 is ON HOLD Authors: Description: Category: Unreleased Structures)
Current revision (07:23, 3 July 2024) (edit) (undo)
 
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'''Unreleased structure'''
 
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The entry 8z50 is ON HOLD
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==Crystal structure of the ASF1-H3T-H4 complex==
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<StructureSection load='8z50' size='340' side='right'caption='[[8z50]], [[Resolution|resolution]] 2.80&Aring;' scene=''>
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Authors:
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== Structural highlights ==
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<table><tr><td colspan='2'>[[8z50]] is a 3 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=8Z50 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=8Z50 FirstGlance]. <br>
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Description:
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.8&#8491;</td></tr>
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[[Category: Unreleased Structures]]
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=8z50 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=8z50 OCA], [https://pdbe.org/8z50 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=8z50 RCSB], [https://www.ebi.ac.uk/pdbsum/8z50 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=8z50 ProSAT]</span></td></tr>
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</table>
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== Function ==
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[https://www.uniprot.org/uniprot/ASF1A_HUMAN ASF1A_HUMAN] Histone chaperone that facilitates histone deposition and histone exchange and removal during nucleosome assembly and disassembly. Cooperates with chromatin assembly factor 1 (CAF-1) to promote replication-dependent chromatin assembly and with HIRA to promote replication-independent chromatin assembly. Required for the formation of senescence-associated heterochromatin foci (SAHF) and efficient senescence-associated cell cycle exit.<ref>PMID:10759893</ref> <ref>PMID:11897662</ref> <ref>PMID:12842904</ref> <ref>PMID:14718166</ref> <ref>PMID:15621527</ref> <ref>PMID:16151251</ref> <ref>PMID:15664198</ref>
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== References ==
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<references/>
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__TOC__
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</StructureSection>
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[[Category: Homo sapiens]]
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[[Category: Large Structures]]
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[[Category: Xu L]]

Current revision

Crystal structure of the ASF1-H3T-H4 complex

PDB ID 8z50

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