9awj
From Proteopedia
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| - | '''Unreleased structure''' | ||
| - | + | ==Bovine adult muscle nAChR bound to ACh== | |
| - | + | <StructureSection load='9awj' size='340' side='right'caption='[[9awj]], [[Resolution|resolution]] 2.45Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[9awj]] is a 5 chain structure with sequence from [https://en.wikipedia.org/wiki/Bos_taurus Bos taurus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=9AWJ OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=9AWJ FirstGlance]. <br> | |
| - | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Electron Microscopy, [[Resolution|Resolution]] 2.45Å</td></tr> | |
| - | [[Category: | + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ACH:ACETYLCHOLINE'>ACH</scene>, <scene name='pdbligand=BMA:BETA-D-MANNOSE'>BMA</scene>, <scene name='pdbligand=MAN:ALPHA-D-MANNOSE'>MAN</scene>, <scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene>, <scene name='pdbligand=POV:(2S)-3-(HEXADECANOYLOXY)-2-[(9Z)-OCTADEC-9-ENOYLOXY]PROPYL+2-(TRIMETHYLAMMONIO)ETHYL+PHOSPHATE'>POV</scene></td></tr> |
| - | [[Category: | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=9awj FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=9awj OCA], [https://pdbe.org/9awj PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=9awj RCSB], [https://www.ebi.ac.uk/pdbsum/9awj PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=9awj ProSAT]</span></td></tr> |
| - | [[Category: Hibbs | + | </table> |
| + | == Function == | ||
| + | [https://www.uniprot.org/uniprot/ACHA_BOVIN ACHA_BOVIN] Upon acetylcholine binding, the AChR responds by an extensive change in conformation that affects all subunits and leads to opening of an ion-conducting channel across the plasma membrane.<ref>PMID:2423878</ref> | ||
| + | == References == | ||
| + | <references/> | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
| + | [[Category: Bos taurus]] | ||
| + | [[Category: Large Structures]] | ||
| + | [[Category: Hibbs RE]] | ||
| + | [[Category: Li H]] | ||
Current revision
Bovine adult muscle nAChR bound to ACh
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