9atw
From Proteopedia
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- | '''Unreleased structure''' | ||
- | + | ==Structure of biofilm-forming functional amyloid PSMa1 from Staphylococcus aureus== | |
- | + | <StructureSection load='9atw' size='340' side='right'caption='[[9atw]], [[Resolution|resolution]] 3.50Å' scene=''> | |
- | + | == Structural highlights == | |
- | + | <table><tr><td colspan='2'>[[9atw]] is a 64 chain structure with sequence from [https://en.wikipedia.org/wiki/Staphylococcus_aureus Staphylococcus aureus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=9ATW OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=9ATW FirstGlance]. <br> | |
- | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Electron Microscopy, [[Resolution|Resolution]] 3.5Å</td></tr> | |
- | [[Category: | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=9atw FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=9atw OCA], [https://pdbe.org/9atw PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=9atw RCSB], [https://www.ebi.ac.uk/pdbsum/9atw PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=9atw ProSAT]</span></td></tr> |
+ | </table> | ||
+ | == Function == | ||
+ | [https://www.uniprot.org/uniprot/PSMA1_STAAW PSMA1_STAAW] Peptide which can recruit, activate and subsequently lyse human neutrophils, thus eliminating the main cellular defense against infection. Stimulates the secretion of the chemotactic factor interleukin-8 (IL-8). The ensuing activation process triggers an inflammatory response in the host, thus contributing greatly to virulence. Also possesses hemolytic activity, which may contribute to the development of disease.<ref>PMID:17994102</ref> | ||
+ | == References == | ||
+ | <references/> | ||
+ | __TOC__ | ||
+ | </StructureSection> | ||
+ | [[Category: Large Structures]] | ||
+ | [[Category: Staphylococcus aureus]] | ||
+ | [[Category: Akbey U]] | ||
+ | [[Category: Andreasen M]] | ||
+ | [[Category: Boesen T]] | ||
+ | [[Category: Byeon CH]] | ||
+ | [[Category: Conway JF]] | ||
+ | [[Category: Drace T]] | ||
+ | [[Category: Hansen KH]] | ||
+ | [[Category: Liu Q]] |
Current revision
Structure of biofilm-forming functional amyloid PSMa1 from Staphylococcus aureus
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Categories: Large Structures | Staphylococcus aureus | Akbey U | Andreasen M | Boesen T | Byeon CH | Conway JF | Drace T | Hansen KH | Liu Q