1s9b

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[[Image:1s9b.gif|left|200px]]
 
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==Crystal Structure Analysis of the B-DNA GAATTCG==
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The line below this paragraph, containing "STRUCTURE_1s9b", creates the "Structure Box" on the page.
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<StructureSection load='1s9b' size='340' side='right'caption='[[1s9b]], [[Resolution|resolution]] 2.81&Aring;' scene=''>
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You may change the PDB parameter (which sets the PDB file loaded into the applet)
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== Structural highlights ==
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or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
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<table><tr><td colspan='2'>[[1s9b]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1S9B OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1S9B FirstGlance]. <br>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.81&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=NI:NICKEL+(II)+ION'>NI</scene></td></tr>
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{{STRUCTURE_1s9b| PDB=1s9b | SCENE= }}
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1s9b FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1s9b OCA], [https://pdbe.org/1s9b PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1s9b RCSB], [https://www.ebi.ac.uk/pdbsum/1s9b PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1s9b ProSAT]</span></td></tr>
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</table>
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'''Crystal Structure Analysis of the B-DNA GAATTCG'''
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__TOC__
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</StructureSection>
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[[Category: Large Structures]]
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==Overview==
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[[Category: Gouyette C]]
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DNA oligonucleotides can be used in order to assemble highly structured materials. Oligonucleotides with sticky ends can form long linear structures, whereas branching is required to form two- and three-dimensional nanostructures. In this paper, we show that when Ni(2+) is attached to the N7 atom of guanine, it can also act as a branching point. Thus, we have found that the heptanucleotide d(GAATTCG) can assemble into long linear duplex structures, which cross in space to generate a cubic structure. The three-dimensional arrays are stabilized by phosphate-Ni(2+)-guanine interactions. For the first time, the crystallization of a B form DNA oligonucleotide in a cubic system is reported, space group I23. Large solvent cavities are found among the DNA duplexes.
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[[Category: Subirana JA]]
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[[Category: Uson I]]
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==About this Structure==
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[[Category: Valls N]]
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Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1S9B OCA].
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==Reference==
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A cubic arrangement of DNA double helices based on nickel-guanine interactions., Valls N, Uson I, Gouyette C, Subirana JA, J Am Chem Soc. 2004 Jun 30;126(25):7812-6. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/15212528 15212528]
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[[Category: Gouyette, C.]]
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[[Category: Subirana, J A.]]
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[[Category: Uson, I.]]
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[[Category: Valls, N.]]
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[[Category: Cubic dna]]
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[[Category: Double helix]]
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[[Category: Nickel]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sat May 3 08:26:36 2008''
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Current revision

Crystal Structure Analysis of the B-DNA GAATTCG

PDB ID 1s9b

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