1saq

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[[Image:1saq.gif|left|200px]]
 
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==Crystal Structure of the RNA octamer GIC(GA)GCC==
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The line below this paragraph, containing "STRUCTURE_1saq", creates the "Structure Box" on the page.
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<StructureSection load='1saq' size='340' side='right'caption='[[1saq]], [[Resolution|resolution]] 2.70&Aring;' scene=''>
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You may change the PDB parameter (which sets the PDB file loaded into the applet)
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== Structural highlights ==
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or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
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<table><tr><td colspan='2'>[[1saq]] is a 5 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1SAQ OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1SAQ FirstGlance]. <br>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.7&#8491;</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1saq FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1saq OCA], [https://pdbe.org/1saq PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1saq RCSB], [https://www.ebi.ac.uk/pdbsum/1saq PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1saq ProSAT]</span></td></tr>
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{{STRUCTURE_1saq| PDB=1saq | SCENE= }}
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</table>
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__TOC__
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'''Crystal Structure of the RNA octamer GIC(GA)GCC'''
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</StructureSection>
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[[Category: Large Structures]]
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[[Category: Baeyens K]]
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==Overview==
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[[Category: Holbrook SR]]
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The crystal structures of two RNA octamers, 5'-GGC(GA)GCC-3' and 5'-GIC(GA)GCC-3', have been determined from X-ray diffraction data to 2.8 and 2.7 A resolution, respectively. The RNA octamers crystallize in isomorphous unit cells containing two mispairs arranged in a self-complementary manner and one single strand in the asymmetric unit. The single strand pairs with another single strand related by crystallographic symmetry to form a third unique double helix. Tandem non-Watson-Crick G.A/A.G base pairs of the sheared type comprise an internal loop in the middle of each duplex. The NMR structure of this octameric RNA sequence is also known, allowing comparison of the variation between the six crystallographic duplexes and the solution structure. In the symmetric duplex of the octamer containing inosine, the sheared G.A pairs incorporate a bound water molecule. This duplex also binds one water molecule per strand in the minor groove adjacent to the G.A pairs.
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[[Category: Jang SB]]
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[[Category: Jeong MS]]
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==About this Structure==
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[[Category: SantaLucia Jr J]]
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Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1SAQ OCA].
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[[Category: Turner D]]
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==Reference==
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Structures of two RNA octamers containing tandem G.A base pairs., Jang SB, Baeyens K, Jeong MS, SantaLucia J Jr, Turner D, Holbrook SR, Acta Crystallogr D Biol Crystallogr. 2004 May;60(Pt 5):829-35. Epub 2004, Apr 21. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/15103128 15103128]
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[[Category: Baeyens, K.]]
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[[Category: Holbrook, S R.]]
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[[Category: Jang, S B.]]
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[[Category: Jeong, M S.]]
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[[Category: Jr, J SantaLucia.]]
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[[Category: Turner, D.]]
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[[Category: Rna double helix]]
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[[Category: Rna tandem g-a base pair]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sat May 3 08:29:21 2008''
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Crystal Structure of the RNA octamer GIC(GA)GCC

PDB ID 1saq

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