8qzt

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Current revision (08:05, 6 November 2024) (edit) (undo)
 
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'''Unreleased structure'''
 
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The entry 8qzt is ON HOLD until Paper Publication
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==Single particle cryo-EM co-structure of E. coli AcrB with bound BDM91531 inhibitor at 3.52 A resolution==
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<StructureSection load='8qzt' size='340' side='right'caption='[[8qzt]], [[Resolution|resolution]] 3.52&Aring;' scene=''>
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Authors: Boernsen, C., Mueller, R.T., Pos, K.M., Frangakis, A.S.
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== Structural highlights ==
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<table><tr><td colspan='2'>[[8qzt]] is a 3 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli_K-12 Escherichia coli K-12]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=8QZT OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=8QZT FirstGlance]. <br>
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Description: Single particle cryo-EM co-structure of E. coli AcrB with bound BDM91531 inhibitor at 3.52 A resolution
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Electron Microscopy, [[Resolution|Resolution]] 3.52&#8491;</td></tr>
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[[Category: Unreleased Structures]]
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=XE9:[3-(3-chloranyl-2-piperazin-1-yl-quinolin-6-yl)phenyl]methanamine'>XE9</scene></td></tr>
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[[Category: Boernsen, C]]
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=8qzt FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=8qzt OCA], [https://pdbe.org/8qzt PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=8qzt RCSB], [https://www.ebi.ac.uk/pdbsum/8qzt PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=8qzt ProSAT]</span></td></tr>
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[[Category: Pos, K.M]]
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</table>
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[[Category: Frangakis, A.S]]
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== Function ==
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[[Category: Mueller, R.T]]
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[https://www.uniprot.org/uniprot/ACRB_ECOLI ACRB_ECOLI] AcrAB is a drug efflux protein with a broad substrate specificity.<ref>PMID:16915237</ref> <ref>PMID:16946072</ref> <ref>PMID:17194213</ref>
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== References ==
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<references/>
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__TOC__
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</StructureSection>
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[[Category: Escherichia coli K-12]]
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[[Category: Large Structures]]
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[[Category: Boernsen C]]
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[[Category: Frangakis AS]]
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[[Category: Mueller RT]]
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[[Category: Pos KM]]

Current revision

Single particle cryo-EM co-structure of E. coli AcrB with bound BDM91531 inhibitor at 3.52 A resolution

PDB ID 8qzt

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