8wss

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Current revision (05:56, 19 June 2024) (edit) (undo)
 
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'''Unreleased structure'''
 
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The entry 8wss is ON HOLD until Paper Publication
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==Cryo-EM structure of Melanin-Concentrating Hormone Receptor 1 with MCH==
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<StructureSection load='8wss' size='340' side='right'caption='[[8wss]], [[Resolution|resolution]] 3.01&Aring;' scene=''>
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Authors: Zhao, L., He, Q., Yuan, Q., Gu, Y., Shan, H., Hu, W., Wu, K., Xu, H.E., Zhang, Y., Wu, C.
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== Structural highlights ==
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<table><tr><td colspan='2'>[[8wss]] is a 6 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens] and [https://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=8WSS OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=8WSS FirstGlance]. <br>
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Description: Cryo-EM structure of Melanin-Concentrating Hormone Receptor 1 with MCH
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Electron Microscopy, [[Resolution|Resolution]] 3.01&#8491;</td></tr>
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[[Category: Unreleased Structures]]
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=8wss FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=8wss OCA], [https://pdbe.org/8wss PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=8wss RCSB], [https://www.ebi.ac.uk/pdbsum/8wss PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=8wss ProSAT]</span></td></tr>
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[[Category: Shan, H]]
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</table>
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[[Category: Xu, H.E]]
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== Function ==
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[[Category: Wu, K]]
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[https://www.uniprot.org/uniprot/GNAI1_HUMAN GNAI1_HUMAN] Guanine nucleotide-binding proteins (G proteins) are involved as modulators or transducers in various transmembrane signaling systems. The G(i) proteins are involved in hormonal regulation of adenylate cyclase: they inhibit the cyclase in response to beta-adrenergic stimuli. The inactive GDP-bound form prevents the association of RGS14 with centrosomes and is required for the translocation of RGS14 from the cytoplasm to the plasma membrane. May play a role in cell division.<ref>PMID:17635935</ref> <ref>PMID:17264214</ref>
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[[Category: Hu, W]]
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== References ==
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[[Category: Wu, C]]
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<references/>
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[[Category: He, Q]]
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__TOC__
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[[Category: Gu, Y]]
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</StructureSection>
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[[Category: Yuan, Q]]
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[[Category: Homo sapiens]]
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[[Category: Zhao, L]]
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[[Category: Large Structures]]
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[[Category: Zhang, Y]]
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[[Category: Mus musculus]]
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[[Category: Gu Y]]
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[[Category: He Q]]
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[[Category: Hu W]]
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[[Category: Shan H]]
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[[Category: Wu C]]
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[[Category: Wu K]]
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[[Category: Xu HE]]
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[[Category: Yuan Q]]
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[[Category: Zhang Y]]
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[[Category: Zhao L]]

Current revision

Cryo-EM structure of Melanin-Concentrating Hormone Receptor 1 with MCH

PDB ID 8wss

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