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1w7b
From Proteopedia
(Difference between revisions)
(New page: 200px<br /> <applet load="1w7b" size="450" color="white" frame="true" align="right" spinBox="true" caption="1w7b, resolution 1.52Å" /> '''ANNEXIN A2: DOES IT...) |
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| - | [[Image:1w7b.gif|left|200px]]<br /> | ||
| - | <applet load="1w7b" size="450" color="white" frame="true" align="right" spinBox="true" | ||
| - | caption="1w7b, resolution 1.52Å" /> | ||
| - | '''ANNEXIN A2: DOES IT INDUCE MEMBRANE AGGREGATION BY A NEW MULTIMERIC STATE OF THE PROTEIN.'''<br /> | ||
| - | == | + | ==Annexin A2: Does it induce membrane aggregation by a new multimeric state of the protein.== |
| - | + | <StructureSection load='1w7b' size='340' side='right'caption='[[1w7b]], [[Resolution|resolution]] 1.52Å' scene=''> | |
| - | [[ | + | == Structural highlights == |
| - | [[ | + | <table><tr><td colspan='2'>[[1w7b]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1W7B OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1W7B FirstGlance]. <br> |
| - | [[ | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.52Å</td></tr> |
| - | [ | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1w7b FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1w7b OCA], [https://pdbe.org/1w7b PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1w7b RCSB], [https://www.ebi.ac.uk/pdbsum/1w7b PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1w7b ProSAT]</span></td></tr> |
| - | [ | + | </table> |
| - | [[ | + | == Function == |
| - | [ | + | [https://www.uniprot.org/uniprot/ANXA2_HUMAN ANXA2_HUMAN] Calcium-regulated membrane-binding protein whose affinity for calcium is greatly enhanced by anionic phospholipids. It binds two calcium ions with high affinity. May be involved in heat-stress response. |
| + | == Evolutionary Conservation == | ||
| + | [[Image:Consurf_key_small.gif|200px|right]] | ||
| + | Check<jmol> | ||
| + | <jmolCheckbox> | ||
| + | <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/w7/1w7b_consurf.spt"</scriptWhenChecked> | ||
| + | <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked> | ||
| + | <text>to colour the structure by Evolutionary Conservation</text> | ||
| + | </jmolCheckbox> | ||
| + | </jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1w7b ConSurf]. | ||
| + | <div style="clear:both"></div> | ||
| - | + | ==See Also== | |
| + | *[[Annexin 3D structures|Annexin 3D structures]] | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
| + | [[Category: Homo sapiens]] | ||
| + | [[Category: Large Structures]] | ||
| + | [[Category: Luecke H]] | ||
| + | [[Category: Rosengarth A]] | ||
Current revision
Annexin A2: Does it induce membrane aggregation by a new multimeric state of the protein.
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