8vof

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'''Unreleased structure'''
 
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The entry 8vof is ON HOLD
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==GI targeted CpPI4K inhibitor==
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<StructureSection load='8vof' size='340' side='right'caption='[[8vof]], [[Resolution|resolution]] 3.00&Aring;' scene=''>
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Authors: Knapp, M.S., Cuellar, C., Mamo, M.
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== Structural highlights ==
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<table><tr><td colspan='2'>[[8vof]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=8VOF OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=8VOF FirstGlance]. <br>
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Description: GI targeted CpPI4K inhibitor
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 3&#8491;</td></tr>
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[[Category: Unreleased Structures]]
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=8vof FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=8vof OCA], [https://pdbe.org/8vof PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=8vof RCSB], [https://www.ebi.ac.uk/pdbsum/8vof PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=8vof ProSAT]</span></td></tr>
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[[Category: Mamo, M]]
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</table>
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[[Category: Knapp, M.S]]
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== Function ==
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[[Category: Cuellar, C]]
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[https://www.uniprot.org/uniprot/PI4KB_HUMAN PI4KB_HUMAN] Phosphorylates phosphatidylinositol (PI) in the first committed step in the production of the second messenger inositol-1,4,5,-trisphosphate (PIP). May regulate Golgi disintegration/reorganization during mitosis, possibly via its phosphorylation. Involved in Golgi-to-plasma membrane trafficking (By similarity).<ref>PMID:9405935</ref> <ref>PMID:10559940</ref> <ref>PMID:12749687</ref>
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== References ==
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<references/>
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__TOC__
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</StructureSection>
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[[Category: Homo sapiens]]
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[[Category: Large Structures]]
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[[Category: Cuellar C]]
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[[Category: Knapp MS]]
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[[Category: Mamo M]]

Current revision

GI targeted CpPI4K inhibitor

PDB ID 8vof

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