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1wfv

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(New page: 200px<br /> <applet load="1wfv" size="450" color="white" frame="true" align="right" spinBox="true" caption="1wfv" /> '''Solution structure of the fifth PDZ domain ...)
Current revision (13:37, 9 May 2024) (edit) (undo)
 
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[[Image:1wfv.gif|left|200px]]<br />
 
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<applet load="1wfv" size="450" color="white" frame="true" align="right" spinBox="true"
 
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caption="1wfv" />
 
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'''Solution structure of the fifth PDZ domain of human membrane associated guanylate kinase inverted-2 (KIAA0705 protein)'''<br />
 
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==About this Structure==
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==Solution structure of the fifth PDZ domain of human membrane associated guanylate kinase inverted-2 (KIAA0705 protein)==
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1WFV is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://ispc.weizmann.ac.il/oca-bin/ocashort?id=1WFV OCA].
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<StructureSection load='1wfv' size='340' side='right'caption='[[1wfv]]' scene=''>
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[[Category: Homo sapiens]]
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== Structural highlights ==
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[[Category: Single protein]]
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<table><tr><td colspan='2'>[[1wfv]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1WFV OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1WFV FirstGlance]. <br>
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[[Category: Inoue, M.]]
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Solution NMR</td></tr>
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[[Category: Kigawa, T.]]
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1wfv FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1wfv OCA], [https://pdbe.org/1wfv PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1wfv RCSB], [https://www.ebi.ac.uk/pdbsum/1wfv PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1wfv ProSAT], [https://www.topsan.org/Proteins/RSGI/1wfv TOPSAN]</span></td></tr>
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[[Category: Koshiba, S.]]
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</table>
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[[Category: RSGI, RIKEN.Structural.Genomics/Proteomics.Initiative.]]
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== Function ==
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[[Category: Tochio, N.]]
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[https://www.uniprot.org/uniprot/MAGI2_HUMAN MAGI2_HUMAN] Seems to act as scaffold molecule at synaptic junctions by assembling neurotransmitter receptors and cell adhesion proteins. May play a role in regulating activin-mediated signaling in neuronal cells. Enhances the ability of PTEN to suppress AKT1 activation.<ref>PMID:10760291</ref>
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[[Category: Yokoyama, S.]]
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== Evolutionary Conservation ==
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[[Category: activin receptor interacting protein 1]]
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[[Image:Consurf_key_small.gif|200px|right]]
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[[Category: activin type iia receptor]]
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Check<jmol>
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[[Category: actriia]]
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<jmolCheckbox>
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[[Category: acvrip1]]
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/wf/1wfv_consurf.spt"</scriptWhenChecked>
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[[Category: aip1]]
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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[[Category: arip1]]
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<text>to colour the structure by Evolutionary Conservation</text>
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[[Category: atrophin-1 interacting protein 1]]
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</jmolCheckbox>
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[[Category: magi-2]]
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1wfv ConSurf].
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[[Category: membrane associated guanylate kinase inverted-2]]
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<div style="clear:both"></div>
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[[Category: pdz domain]]
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[[Category: riken structural genomics/proteomics initiative]]
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[[Category: rsgi]]
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[[Category: structural genomics]]
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''Page seeded by [http://ispc.weizmann.ac.il/oca OCA ] on Mon Nov 12 19:50:11 2007''
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==See Also==
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*[[Guanylate kinase 3D structures|Guanylate kinase 3D structures]]
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== References ==
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<references/>
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__TOC__
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</StructureSection>
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[[Category: Homo sapiens]]
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[[Category: Large Structures]]
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[[Category: Inoue M]]
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[[Category: Kigawa T]]
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[[Category: Koshiba S]]
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[[Category: Tochio N]]
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[[Category: Yokoyama S]]

Current revision

Solution structure of the fifth PDZ domain of human membrane associated guanylate kinase inverted-2 (KIAA0705 protein)

PDB ID 1wfv

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