9ij9
From Proteopedia
(Difference between revisions)
(New page: '''Unreleased structure''' The entry 9ij9 is ON HOLD Authors: Yuan, Q., Duan, J., Tao, L., Xu, E.H. Description: A local Cryo-EM structure of Bitter taste receptor TAS2R14 of TAS2R14 w...) |
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| - | '''Unreleased structure''' | ||
| - | + | ==A Cryo-EM structure of Bitter taste receptor TAS2R14 with Gi complex== | |
| - | + | <StructureSection load='9ij9' size='340' side='right'caption='[[9ij9]], [[Resolution|resolution]] 2.70Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[9ij9]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=9IJ9 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=9IJ9 FirstGlance]. <br> | |
| - | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Electron Microscopy, [[Resolution|Resolution]] 2.7Å</td></tr> | |
| - | [[Category: | + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=A1AEI:4-methyl-N-[(2M)-2-(1H-tetrazol-5-yl)phenyl]-6-(trifluoromethyl)pyrimidin-2-amine'>A1AEI</scene>, <scene name='pdbligand=CLR:CHOLESTEROL'>CLR</scene></td></tr> |
| - | [[Category: | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=9ij9 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=9ij9 OCA], [https://pdbe.org/9ij9 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=9ij9 RCSB], [https://www.ebi.ac.uk/pdbsum/9ij9 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=9ij9 ProSAT]</span></td></tr> |
| - | [[Category: Tao | + | </table> |
| - | [[Category: | + | == Function == |
| - | [[Category: | + | [https://www.uniprot.org/uniprot/GNAI1_HUMAN GNAI1_HUMAN] Guanine nucleotide-binding proteins (G proteins) are involved as modulators or transducers in various transmembrane signaling systems. The G(i) proteins are involved in hormonal regulation of adenylate cyclase: they inhibit the cyclase in response to beta-adrenergic stimuli. The inactive GDP-bound form prevents the association of RGS14 with centrosomes and is required for the translocation of RGS14 from the cytoplasm to the plasma membrane. May play a role in cell division.<ref>PMID:17635935</ref> <ref>PMID:17264214</ref> |
| + | == References == | ||
| + | <references/> | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
| + | [[Category: Homo sapiens]] | ||
| + | [[Category: Large Structures]] | ||
| + | [[Category: Duan J]] | ||
| + | [[Category: Tao L]] | ||
| + | [[Category: Xu EH]] | ||
| + | [[Category: Yuan Q]] | ||
Current revision
A Cryo-EM structure of Bitter taste receptor TAS2R14 with Gi complex
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Categories: Homo sapiens | Large Structures | Duan J | Tao L | Xu EH | Yuan Q
