Nucleoside triphosphatase

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'''Nucleoside triphosphatase''' or '''nucleoside triphosphate diphosphohydrolase''' (NTPase) is responsible for degradation of nucleotides to their monophosphate form. NTPase is found in mammals and in pathogenic microbes. In mammals NTPase hs a crucial role in regulation of purinergic signalling by hydrolysis of extracellular nucleotides. The function of NTPase in pathogens is still unknown<ref>PMID:24115522</ref>.
'''Nucleoside triphosphatase''' or '''nucleoside triphosphate diphosphohydrolase''' (NTPase) is responsible for degradation of nucleotides to their monophosphate form. NTPase is found in mammals and in pathogenic microbes. In mammals NTPase hs a crucial role in regulation of purinergic signalling by hydrolysis of extracellular nucleotides. The function of NTPase in pathogens is still unknown<ref>PMID:24115522</ref>.
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*'''Nucleoside triphosphatase Nudi''' catalyses the hydrolysis of preferentially dUTP, dTTP and dCTP.
== Relevance ==
== Relevance ==
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==3D structures of nucleoside triphosphatase==
==3D structures of nucleoside triphosphatase==
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[[Nucleoside triphosphatase 3D structures]]
[[Nucleoside triphosphatase 3D structures]]

Current revision

NTPase 2 tetramer complex with AMPPNP and Mg++ ion (green) (PDB entry 4a5a)

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