9cz8
From Proteopedia
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| - | '''Unreleased structure''' | ||
| - | + | ==Structure of thioferritin exhibiting iron mineral nucleation, from Pyrococcus furiosis== | |
| - | + | <StructureSection load='9cz8' size='340' side='right'caption='[[9cz8]], [[Resolution|resolution]] 1.91Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[9cz8]] is a 12 chain structure with sequence from [https://en.wikipedia.org/wiki/Pyrococcus_furiosus Pyrococcus furiosus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=9CZ8 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=9CZ8 FirstGlance]. <br> | |
| - | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Electron Microscopy, [[Resolution|Resolution]] 1.91Å</td></tr> | |
| - | [[Category: | + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=FE:FE+(III)+ION'>FE</scene>, <scene name='pdbligand=O:OXYGEN+ATOM'>O</scene></td></tr> |
| + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=9cz8 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=9cz8 OCA], [https://pdbe.org/9cz8 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=9cz8 RCSB], [https://www.ebi.ac.uk/pdbsum/9cz8 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=9cz8 ProSAT]</span></td></tr> | ||
| + | </table> | ||
| + | == Function == | ||
| + | [https://www.uniprot.org/uniprot/DPS_PYRFU DPS_PYRFU] Protects DNA from oxidative damage by sequestering intracellular Fe(2+) ion and storing it in the form of Fe(3+) oxyhydroxide mineral. One hydrogen peroxide oxidizes two Fe(2+) ions, which prevents hydroxyl radical production by the Fenton reaction (By similarity). It efficiently oxidizes Fe(2+) in the presence of hydrogen peroxide and stores it. | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
| + | [[Category: Large Structures]] | ||
| + | [[Category: Pyrococcus furiosus]] | ||
| + | [[Category: Bothner B]] | ||
| + | [[Category: Douglas T]] | ||
| + | [[Category: Gauvin CC]] | ||
| + | [[Category: Lawrence CM]] | ||
| + | [[Category: Tokmina-Lukaszewska M]] | ||
| + | [[Category: Waghwani HK]] | ||
Current revision
Structure of thioferritin exhibiting iron mineral nucleation, from Pyrococcus furiosis
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