9d03
From Proteopedia
(Difference between revisions)
(New page: '''Unreleased structure''' The entry 9d03 is ON HOLD Authors: Delker, S.L., Edwards, T.E., Abendroth, J. Description: Co-crystal structure of circularly permuted human taspase-1 bound ...) |
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| - | '''Unreleased structure''' | ||
| - | + | ==Co-crystal structure of circularly permuted human taspase-1 bound to ligand SMDC1014689 1-(ethenesulfonyl)-4-{[3-fluoro-4-(trifluoromethoxy)phenyl]methyl}piperazine== | |
| - | + | <StructureSection load='9d03' size='340' side='right'caption='[[9d03]], [[Resolution|resolution]] 2.45Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[9d03]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=9D03 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=9D03 FirstGlance]. <br> | |
| - | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.45Å</td></tr> | |
| - | [[ | + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=NA:SODIUM+ION'>NA</scene>, <scene name='pdbligand=R1M:1-(ethenylsulfonyl)-4-{[3-fluoro-4-(trifluoromethoxy)phenyl]methyl}piperazine'>R1M</scene></td></tr> |
| - | [[ | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=9d03 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=9d03 OCA], [https://pdbe.org/9d03 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=9d03 RCSB], [https://www.ebi.ac.uk/pdbsum/9d03 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=9d03 ProSAT]</span></td></tr> |
| - | [[Category: Abendroth | + | </table> |
| - | [[Category: Edwards | + | == Function == |
| + | [https://www.uniprot.org/uniprot/TASP1_HUMAN TASP1_HUMAN] Protease involved in MLL processing and, consequently, in the correct expression of the early HOXA gene cluster. | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
| + | [[Category: Homo sapiens]] | ||
| + | [[Category: Large Structures]] | ||
| + | [[Category: Abendroth J]] | ||
| + | [[Category: Delker SL]] | ||
| + | [[Category: Edwards TE]] | ||
Current revision
Co-crystal structure of circularly permuted human taspase-1 bound to ligand SMDC1014689 1-(ethenesulfonyl)-4-{[3-fluoro-4-(trifluoromethoxy)phenyl]methyl}piperazine
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