T-cell receptor
From Proteopedia
(Difference between revisions)
| (One intermediate revision not shown.) | |||
| Line 2: | Line 2: | ||
__TOC__ | __TOC__ | ||
== Function == | == Function == | ||
| - | '''T-cell receptors''' (TCR) reside on the surface of T lymphocytes. TCR recognizes antigens bound to major histocompatibility complex (MHC) molecules. The binding of TCR to the antigen-MHC activates the T lymphocytes<ref>PMID:17624994</ref>. TCR is a heterodimer of α+β subunits and ca. 5% the T cells have | + | '''T-cell receptors''' (TCR) reside on the surface of T lymphocytes. TCR recognizes antigens bound to major histocompatibility complex (MHC) molecules. The binding of TCR to the antigen-MHC activates the T lymphocytes<ref>PMID:17624994</ref>. TCR is a heterodimer of '''α+β subunits''' and ca. 5% the T cells have '''γ+δ subumits'''. '''TCR NKT''' reside in Natural Killer T-cells. |
*<scene name='53/536684/Cv/3'>T-cell receptor α chain, β chain complex with enterotoxin and Na+ ion</scene> ([[2xna]]). | *<scene name='53/536684/Cv/3'>T-cell receptor α chain, β chain complex with enterotoxin and Na+ ion</scene> ([[2xna]]). | ||
Current revision
| |||||||||||
References
- ↑ Kang L, Sebastian BM, Pritchard MT, Pratt BT, Previs SF, Nagy LE. Chronic ethanol-induced insulin resistance is associated with macrophage infiltration into adipose tissue and altered expression of adipocytokines. Alcohol Clin Exp Res. 2007 Sep;31(9):1581-8. Epub 2007 Jul 11. PMID:17624994 doi:http://dx.doi.org/10.1111/j.1530-0277.2007.00452.x
- ↑ Uttenthal BJ, Chua I, Morris EC, Stauss HJ. Challenges in T cell receptor gene therapy. J Gene Med. 2012 Jun;14(6):386-99. doi: 10.1002/jgm.2637. PMID:22610778 doi:http://dx.doi.org/10.1002/jgm.2637
Proteopedia Page Contributors and Editors (what is this?)
Michal Harel, Alexander Berchansky, Joel L. Sussman, Jaime Prilusky
