8sii

From Proteopedia

(Difference between revisions)
Jump to: navigation, search
Current revision (05:35, 4 September 2024) (edit) (undo)
 
Line 1: Line 1:
-
'''Unreleased structure'''
 
-
The entry 8sii is ON HOLD until Paper Publication
+
==Crystal Structure of CBX7 with compound UNC4976==
-
 
+
<StructureSection load='8sii' size='340' side='right'caption='[[8sii]], [[Resolution|resolution]] 1.37&Aring;' scene=''>
-
Authors: Song, X., Dong, A., Huang, R., Arrowsmith, C.H., Edwards, A.M., Min, J., Structural Genomics Consortium (SGC)
+
== Structural highlights ==
-
 
+
<table><tr><td colspan='2'>[[8sii]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens] and [https://en.wikipedia.org/wiki/Synthetic_construct Synthetic construct]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=8SII OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=8SII FirstGlance]. <br>
-
Description: Crystal Structure of CBX7 with compound UNC4976
+
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.37&#8491;</td></tr>
-
[[Category: Unreleased Structures]]
+
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=8sii FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=8sii OCA], [https://pdbe.org/8sii PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=8sii RCSB], [https://www.ebi.ac.uk/pdbsum/8sii PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=8sii ProSAT]</span></td></tr>
-
[[Category: Song, X]]
+
</table>
-
[[Category: Arrowsmith, C.H]]
+
== Function ==
-
[[Category: Dong, A]]
+
[https://www.uniprot.org/uniprot/CBX7_HUMAN CBX7_HUMAN] Component of a Polycomb group (PcG) multiprotein PRC1-like complex, a complex class required to maintain the transcriptionally repressive state of many genes, including Hox genes, throughout development. PcG PRC1 complex acts via chromatin remodeling and modification of histones; it mediates monoubiquitination of histone H2A 'Lys-119', rendering chromatin heritably changed in its expressibility. Promotes histone H3 trimethylation at 'Lys-9' (H3K9me3). Binds to trimethylated lysine residues in histones, and possibly also other proteins. Regulator of cellular lifespan by maintaining the repression of CDKN2A, but not by inducing telomerase activity.<ref>PMID:19636380</ref> <ref>PMID:21060834</ref> <ref>PMID:21282530</ref> <ref>PMID:21047797</ref>
-
[[Category: Edwards, A.M]]
+
== References ==
-
[[Category: Min, J]]
+
<references/>
-
[[Category: Huang, R]]
+
__TOC__
-
[[Category: Structural Genomics Consortium (Sgc)]]
+
</StructureSection>
 +
[[Category: Homo sapiens]]
 +
[[Category: Large Structures]]
 +
[[Category: Synthetic construct]]
 +
[[Category: Arrowsmith CH]]
 +
[[Category: Dong A]]
 +
[[Category: Edwards AM]]
 +
[[Category: Huang R]]
 +
[[Category: Min J]]
 +
[[Category: Song X]]

Current revision

Crystal Structure of CBX7 with compound UNC4976

PDB ID 8sii

Drag the structure with the mouse to rotate

Proteopedia Page Contributors and Editors (what is this?)

OCA

Retrieved from "http://52.214.119.220/wiki/index.php/8sii"
Personal tools