9d9n
From Proteopedia
(Difference between revisions)
(New page: '''Unreleased structure''' The entry 9d9n is ON HOLD Authors: Jacobs, L.M.C., Chen, Y. Description: Crystal structure of NDM-1 complexed with compound 5 [[Category: Unreleased Structur...) |
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| - | '''Unreleased structure''' | ||
| - | + | ==Crystal structure of NDM-1 complexed with compound 5== | |
| - | + | <StructureSection load='9d9n' size='340' side='right'caption='[[9d9n]], [[Resolution|resolution]] 1.68Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[9d9n]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Klebsiella_pneumoniae Klebsiella pneumoniae]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=9D9N OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=9D9N FirstGlance]. <br> | |
| - | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.68Å</td></tr> | |
| - | [[Category: | + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=A1A25:{[1-methyl-2-oxo-7-(pyrrolidin-1-yl)-1,2-dihydroquinolin-4-yl]methyl}phosphonic+acid'>A1A25</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr> |
| - | [[Category: Chen | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=9d9n FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=9d9n OCA], [https://pdbe.org/9d9n PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=9d9n RCSB], [https://www.ebi.ac.uk/pdbsum/9d9n PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=9d9n ProSAT]</span></td></tr> |
| - | [[Category: Jacobs | + | </table> |
| + | == Function == | ||
| + | [https://www.uniprot.org/uniprot/BLAN1_KLEPN BLAN1_KLEPN] Confers resistance to many beta-lactam antibiotics, including some carbapenems. Does not confer resistance to the polymixin colistin or the fluoroquinolone ciprofloxacin. | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
| + | [[Category: Klebsiella pneumoniae]] | ||
| + | [[Category: Large Structures]] | ||
| + | [[Category: Chen Y]] | ||
| + | [[Category: Jacobs LMC]] | ||
Current revision
Crystal structure of NDM-1 complexed with compound 5
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