9j7y
From Proteopedia
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| - | '''Unreleased structure''' | ||
| - | + | ==the complex structure of MPXV M1R and nanobody M1R-01== | |
| - | + | <StructureSection load='9j7y' size='340' side='right'caption='[[9j7y]], [[Resolution|resolution]] 2.59Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[9j7y]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Monkeypox_virus Monkeypox virus] and [https://en.wikipedia.org/wiki/Synthetic_construct Synthetic construct]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=9J7Y OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=9J7Y FirstGlance]. <br> | |
| - | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.59Å</td></tr> | |
| - | [[Category: | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=9j7y FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=9j7y OCA], [https://pdbe.org/9j7y PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=9j7y RCSB], [https://www.ebi.ac.uk/pdbsum/9j7y PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=9j7y ProSAT]</span></td></tr> |
| + | </table> | ||
| + | == Function == | ||
| + | [https://www.uniprot.org/uniprot/PG095_MONPV PG095_MONPV] Component of the entry fusion complex (EFC), which consists of 11 proteins. During cell infection, this complex mediates entry of the virion core into the host cytoplasm by a two-step mechanism consisting of lipid mixing of the viral and cellular membranes and subsequent pore formation.[UniProtKB:P07612] | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
| + | [[Category: Large Structures]] | ||
| + | [[Category: Monkeypox virus]] | ||
| + | [[Category: Synthetic construct]] | ||
| + | [[Category: Fan M]] | ||
| + | [[Category: Ge JW]] | ||
Current revision
the complex structure of MPXV M1R and nanobody M1R-01
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