9jgk
From Proteopedia
(Difference between revisions)
(New page: '''Unreleased structure''' The entry 9jgk is ON HOLD Authors: Kaixuan, G., Xin, Z., Xiangyu, L. Description: cryo-EM structure of 5-Hydroxytryptamine 2B Receptor in complex with balova...) |
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| - | '''Unreleased structure''' | ||
| - | + | ==cryo-EM structure of 5-Hydroxytryptamine 2B Receptor in complex with balovaptan== | |
| - | + | <StructureSection load='9jgk' size='340' side='right'caption='[[9jgk]], [[Resolution|resolution]] 3.60Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[9jgk]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli], [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens] and [https://en.wikipedia.org/wiki/Synthetic_construct Synthetic construct]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=9JGK OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=9JGK FirstGlance]. <br> | |
| - | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Electron Microscopy, [[Resolution|Resolution]] 3.6Å</td></tr> | |
| - | [[Category: | + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=A1EB7:8-chloranyl-5-methyl-1-(4-pyridin-2-yloxycyclohexyl)-4,6-dihydro-[1,2,4]triazolo[4,3-a][1,4]benzodiazepine'>A1EB7</scene></td></tr> |
| - | [[Category: | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=9jgk FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=9jgk OCA], [https://pdbe.org/9jgk PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=9jgk RCSB], [https://www.ebi.ac.uk/pdbsum/9jgk PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=9jgk ProSAT]</span></td></tr> |
| - | [[Category: | + | </table> |
| - | [[Category: | + | == Function == |
| + | [https://www.uniprot.org/uniprot/C562_ECOLX C562_ECOLX] Electron-transport protein of unknown function.[https://www.uniprot.org/uniprot/5HT2B_HUMAN 5HT2B_HUMAN] This is one of the several different receptors for 5-hydroxytryptamine (serotonin), a biogenic hormone that functions as a neurotransmitter, a hormone, and a mitogen. This receptor mediates its action by association with G proteins that activate a phosphatidylinositol-calcium second messenger system. Plays a role in the regulation of impulsive behavior. | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
| + | [[Category: Escherichia coli]] | ||
| + | [[Category: Homo sapiens]] | ||
| + | [[Category: Large Structures]] | ||
| + | [[Category: Synthetic construct]] | ||
| + | [[Category: Gao K]] | ||
| + | [[Category: Liu X]] | ||
| + | [[Category: Zhang X]] | ||
Current revision
cryo-EM structure of 5-Hydroxytryptamine 2B Receptor in complex with balovaptan
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