9jrz

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'''Unreleased structure'''
 
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The entry 9jrz is ON HOLD
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==Crystal Structure of 5'-Deoxy-5'-methylthioadenosine phosphorylase from Aeropyrum pernix complex with 5'-Deoxy-5'-methylthioadenosine 323K==
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<StructureSection load='9jrz' size='340' side='right'caption='[[9jrz]], [[Resolution|resolution]] 1.69&Aring;' scene=''>
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Authors: Iizuka, Y., Kikuchi, M., Yamauchi, T., Tsunoda, M.
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== Structural highlights ==
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<table><tr><td colspan='2'>[[9jrz]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Aeropyrum_pernix_K1 Aeropyrum pernix K1]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=9JRZ OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=9JRZ FirstGlance]. <br>
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Description: Crystal Structure of 5''-Deoxy-5''-methylthioadenosine phosphorylase from Aeropyrum pernix complex with 5''-Deoxy-5''-methylthioadenosine 323K
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.69&#8491;</td></tr>
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[[Category: Unreleased Structures]]
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=MTA:5-DEOXY-5-METHYLTHIOADENOSINE'>MTA</scene>, <scene name='pdbligand=PEG:DI(HYDROXYETHYL)ETHER'>PEG</scene>, <scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene></td></tr>
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[[Category: Kikuchi, M]]
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=9jrz FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=9jrz OCA], [https://pdbe.org/9jrz PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=9jrz RCSB], [https://www.ebi.ac.uk/pdbsum/9jrz PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=9jrz ProSAT]</span></td></tr>
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[[Category: Yamauchi, T]]
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</table>
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[[Category: Iizuka, Y]]
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== Function ==
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[[Category: Tsunoda, M]]
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[https://www.uniprot.org/uniprot/MTAP_AERPE MTAP_AERPE] Catalyzes the reversible phosphorylation of S-methyl-5'-thioadenosine (MTA) to adenine and 5-methylthioribose-1-phosphate. Involved in the breakdown of MTA, a major by-product of polyamine biosynthesis. Responsible for the first step in the methionine salvage pathway after MTA has been generated from S-adenosylmethionine. Has broad substrate specificity with 6-aminopurine nucleosides as preferred substrates.[HAMAP-Rule:MF_01963]
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__TOC__
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</StructureSection>
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[[Category: Aeropyrum pernix K1]]
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[[Category: Large Structures]]
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[[Category: Iizuka Y]]
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[[Category: Kikuchi M]]
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[[Category: Tsunoda M]]
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[[Category: Yamauchi T]]

Current revision

Crystal Structure of 5'-Deoxy-5'-methylthioadenosine phosphorylase from Aeropyrum pernix complex with 5'-Deoxy-5'-methylthioadenosine 323K

PDB ID 9jrz

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