9jvp
From Proteopedia
(Difference between revisions)
(New page: '''Unreleased structure''' The entry 9jvp is ON HOLD Authors: Zhou, B., Zhao, H., Gao, Y., Chen, X., Zhang, T., He, J., Xiong, X. Description: CryoEM structure of M. tuberculosis ClpC1...) |
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| - | '''Unreleased structure''' | ||
| - | + | ==CryoEM structure of M. tuberculosis ClpC1P1P2 complex bound to bortezomib, conformation 3== | |
| - | + | <StructureSection load='9jvp' size='340' side='right'caption='[[9jvp]], [[Resolution|resolution]] 2.15Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[9jvp]] is a 21 chain structure with sequence from [https://en.wikipedia.org/wiki/Bos_grunniens Bos grunniens] and [https://en.wikipedia.org/wiki/Mycobacterium_tuberculosis_H37Rv Mycobacterium tuberculosis H37Rv]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=9JVP OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=9JVP FirstGlance]. <br> | |
| - | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Electron Microscopy, [[Resolution|Resolution]] 2.15Å</td></tr> | |
| - | [[Category: | + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ADP:ADENOSINE-5-DIPHOSPHATE'>ADP</scene>, <scene name='pdbligand=ATP:ADENOSINE-5-TRIPHOSPHATE'>ATP</scene>, <scene name='pdbligand=BO2:N-[(1R)-1-(DIHYDROXYBORYL)-3-METHYLBUTYL]-N-(PYRAZIN-2-YLCARBONYL)-L-PHENYLALANINAMIDE'>BO2</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr> |
| - | [[Category: | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=9jvp FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=9jvp OCA], [https://pdbe.org/9jvp PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=9jvp RCSB], [https://www.ebi.ac.uk/pdbsum/9jvp PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=9jvp ProSAT]</span></td></tr> |
| - | [[Category: Gao | + | </table> |
| - | [[Category: He | + | == Function == |
| - | [[Category: | + | [https://www.uniprot.org/uniprot/CLPC1_MYCTU CLPC1_MYCTU] ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP (By similarity). Degrades anti-sigma-E factor RseA in the presence of ClpP2. |
| - | [[Category: | + | __TOC__ |
| - | [[Category: | + | </StructureSection> |
| - | [[Category: | + | [[Category: Bos grunniens]] |
| + | [[Category: Large Structures]] | ||
| + | [[Category: Mycobacterium tuberculosis H37Rv]] | ||
| + | [[Category: Chen X]] | ||
| + | [[Category: Gao Y]] | ||
| + | [[Category: He J]] | ||
| + | [[Category: Xiong X]] | ||
| + | [[Category: Zhang T]] | ||
| + | [[Category: Zhao H]] | ||
| + | [[Category: Zhou B]] | ||
Current revision
CryoEM structure of M. tuberculosis ClpC1P1P2 complex bound to bortezomib, conformation 3
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Categories: Bos grunniens | Large Structures | Mycobacterium tuberculosis H37Rv | Chen X | Gao Y | He J | Xiong X | Zhang T | Zhao H | Zhou B
