9jxv
From Proteopedia
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| - | '''Unreleased structure''' | ||
| - | + | ==human translocase of the outer mitochondrial membrane (TOM complex)== | |
| - | + | <StructureSection load='9jxv' size='340' side='right'caption='[[9jxv]], [[Resolution|resolution]] 2.89Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[9jxv]] is a 10 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=9JXV OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=9JXV FirstGlance]. <br> | |
| - | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Electron Microscopy, [[Resolution|Resolution]] 2.89Å</td></tr> | |
| - | [[Category: | + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=PC1:1,2-DIACYL-SN-GLYCERO-3-PHOSPHOCHOLINE'>PC1</scene></td></tr> |
| + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=9jxv FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=9jxv OCA], [https://pdbe.org/9jxv PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=9jxv RCSB], [https://www.ebi.ac.uk/pdbsum/9jxv PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=9jxv ProSAT]</span></td></tr> | ||
| + | </table> | ||
| + | == Disease == | ||
| + | [https://www.uniprot.org/uniprot/TOM40_HUMAN TOM40_HUMAN] Early-onset autosomal dominant Alzheimer disease. | ||
| + | == Function == | ||
| + | [https://www.uniprot.org/uniprot/TOM40_HUMAN TOM40_HUMAN] Channel-forming protein essential for import of protein precursors into mitochondria (PubMed:15644312, PubMed:31206022). Plays a role in the assembly of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) by forming a complex with BCAP31 and mediating the translocation of Complex I components from the cytosol to the mitochondria (PubMed:31206022).<ref>PMID:15644312</ref> <ref>PMID:31206022</ref> | ||
| + | == References == | ||
| + | <references/> | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
| + | [[Category: Homo sapiens]] | ||
| + | [[Category: Large Structures]] | ||
| + | [[Category: Wang WH]] | ||
| + | [[Category: Yang MJ]] | ||
Current revision
human translocase of the outer mitochondrial membrane (TOM complex)
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