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9h6p
From Proteopedia
(Difference between revisions)
(New page: '''Unreleased structure''' The entry 9h6p is ON HOLD Authors: Balikci, E., Koekemoer, L., Dlamini, L.S., Gurav, N., Apostolidou, M., Adcock, C., McGown, A., Marques, A.M.C., Spencer, J....) |
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| - | '''Unreleased structure''' | ||
| - | + | ==Crystal structure of NUDT14 complexed with novel compound AMNUDT14-003 in spacegroup P1== | |
| - | + | <StructureSection load='9h6p' size='340' side='right'caption='[[9h6p]], [[Resolution|resolution]] 3.16Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[9h6p]] is a 8 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=9H6P OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=9H6P FirstGlance]. <br> | |
| - | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 3.162Å</td></tr> | |
| - | [[Category: | + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=A1ISQ:3-(1~{H}-indol-6-yl)-1-(1-methylpiperidin-4-yl)pyrazolo[3,4-d]pyrimidin-4-amine'>A1ISQ</scene></td></tr> |
| - | [[Category: | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=9h6p FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=9h6p OCA], [https://pdbe.org/9h6p PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=9h6p RCSB], [https://www.ebi.ac.uk/pdbsum/9h6p PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=9h6p ProSAT]</span></td></tr> |
| - | [[Category: | + | </table> |
| - | [[Category: | + | == Function == |
| - | [[Category: | + | [https://www.uniprot.org/uniprot/NUD14_HUMAN NUD14_HUMAN] Hydrolyzes UDP-glucose to glucose 1-phosphate and UMP and ADP-ribose to ribose 5-phosphate and AMP. The physiological substrate is probably UDP-glucose. Poor activity on other substrates such as ADP-glucose, CDP-glucose, GDP-glucose and GDP-mannose. |
| - | [[Category: | + | __TOC__ |
| - | [[Category: | + | </StructureSection> |
| - | [[Category: | + | [[Category: Homo sapiens]] |
| - | [[Category: | + | [[Category: Large Structures]] |
| - | [[Category: | + | [[Category: Adcock C]] |
| - | [[Category: | + | [[Category: Apostolidou M]] |
| + | [[Category: Balikci E]] | ||
| + | [[Category: Dlamini LS]] | ||
| + | [[Category: Gurav N]] | ||
| + | [[Category: Huber KVM]] | ||
| + | [[Category: Koekemoer L]] | ||
| + | [[Category: Marques AMC]] | ||
| + | [[Category: McGown A]] | ||
| + | [[Category: Spencer J]] | ||
Current revision
Crystal structure of NUDT14 complexed with novel compound AMNUDT14-003 in spacegroup P1
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Categories: Homo sapiens | Large Structures | Adcock C | Apostolidou M | Balikci E | Dlamini LS | Gurav N | Huber KVM | Koekemoer L | Marques AMC | McGown A | Spencer J
