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1tvj

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[[Image:1tvj.gif|left|200px]]
 
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==Solution Structure of chick cofilin==
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The line below this paragraph, containing "STRUCTURE_1tvj", creates the "Structure Box" on the page.
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<StructureSection load='1tvj' size='340' side='right'caption='[[1tvj]]' scene=''>
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You may change the PDB parameter (which sets the PDB file loaded into the applet)
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== Structural highlights ==
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or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
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<table><tr><td colspan='2'>[[1tvj]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Gallus_gallus Gallus gallus]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1TVJ OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1TVJ FirstGlance]. <br>
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or leave the SCENE parameter empty for the default display.
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Solution NMR</td></tr>
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-->
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1tvj FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1tvj OCA], [https://pdbe.org/1tvj PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1tvj RCSB], [https://www.ebi.ac.uk/pdbsum/1tvj PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1tvj ProSAT]</span></td></tr>
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{{STRUCTURE_1tvj| PDB=1tvj | SCENE= }}
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</table>
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== Function ==
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'''Solution Structure of chick cofilin'''
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[https://www.uniprot.org/uniprot/COF2_CHICK COF2_CHICK] Controls reversibly actin polymerization and depolymerization in a pH-sensitive manner. It has the ability to bind G- and F-actin in a 1:1 ratio of cofilin to actin. It is the major component of intranuclear and cytoplasmic actin rods.
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== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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==About this Structure==
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Check<jmol>
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1TVJ is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Gallus_gallus Gallus gallus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1TVJ OCA].
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<jmolCheckbox>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/tv/1tvj_consurf.spt"</scriptWhenChecked>
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==Reference==
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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Backbone and side-chain 1H, 15N, and 13C assignments for chick cofilin., Bains NP, Gorbatyuk VY, Nosworthy NJ, Robson SA, Maciejewski MW, dos Remedios CG, King GF, J Biomol NMR. 2002 Feb;22(2):193-4. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/11885570 11885570]
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<text>to colour the structure by Evolutionary Conservation</text>
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</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1tvj ConSurf].
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<div style="clear:both"></div>
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__TOC__
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</StructureSection>
[[Category: Gallus gallus]]
[[Category: Gallus gallus]]
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[[Category: Single protein]]
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[[Category: Large Structures]]
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[[Category: Gorbatyuk, V Y.]]
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[[Category: Gorbatyuk VY]]
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[[Category: King, G F.]]
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[[Category: King GF]]
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[[Category: Maciejewski, M W.]]
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[[Category: Maciejewski MW]]
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[[Category: Nosworthy, N J.]]
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[[Category: Nosworthy NJ]]
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[[Category: Remedios, C G.dos.]]
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[[Category: Robson SA]]
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[[Category: Robson, S A.]]
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[[Category: Dos Remedios CG]]
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[[Category: Actin binding protein]]
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[[Category: Actin depolymerizing factor]]
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[[Category: Adf]]
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[[Category: Cofilin]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sat May 3 10:25:17 2008''
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Current revision

Solution Structure of chick cofilin

PDB ID 1tvj

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