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1u3i

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[[Image:1u3i.gif|left|200px]]
 
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==Crystal structure of glutathione S-tranferase from Schistosoma mansoni==
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The line below this paragraph, containing "STRUCTURE_1u3i", creates the "Structure Box" on the page.
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<StructureSection load='1u3i' size='340' side='right'caption='[[1u3i]], [[Resolution|resolution]] 1.89&Aring;' scene=''>
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You may change the PDB parameter (which sets the PDB file loaded into the applet)
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== Structural highlights ==
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or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
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<table><tr><td colspan='2'>[[1u3i]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Schistosoma_mansoni Schistosoma mansoni]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1U3I OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1U3I FirstGlance]. <br>
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or leave the SCENE parameter empty for the default display.
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.89&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=GSH:GLUTATHIONE'>GSH</scene></td></tr>
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{{STRUCTURE_1u3i| PDB=1u3i | SCENE= }}
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1u3i FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1u3i OCA], [https://pdbe.org/1u3i PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1u3i RCSB], [https://www.ebi.ac.uk/pdbsum/1u3i PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1u3i ProSAT]</span></td></tr>
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</table>
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== Function ==
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[https://www.uniprot.org/uniprot/GST28_SCHMA GST28_SCHMA] Conjugation of reduced glutathione to a wide number of exogenous and endogenous hydrophobic electrophiles. GST isoenzymes appear to play a central role in the parasite detoxification system. Other functions are also suspected including a role in increasing the solubility of haematin in the parasite gut.
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== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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Check<jmol>
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<jmolCheckbox>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/u3/1u3i_consurf.spt"</scriptWhenChecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<text>to colour the structure by Evolutionary Conservation</text>
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</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1u3i ConSurf].
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<div style="clear:both"></div>
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'''Crystal structure of glutathione S-tranferase from Schistosoma mansoni'''
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==See Also==
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*[[Glutathione S-transferase 3D structures|Glutathione S-transferase 3D structures]]
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__TOC__
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==About this Structure==
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</StructureSection>
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1U3I is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Schistosoma_mansoni Schistosoma mansoni]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1U3I OCA].
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[[Category: Large Structures]]
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[[Category: Glutathione transferase]]
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[[Category: Schistosoma mansoni]]
[[Category: Schistosoma mansoni]]
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[[Category: Single protein]]
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[[Category: Capron A]]
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[[Category: Capron, A.]]
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[[Category: Chomilier J]]
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[[Category: Chomilier, J.]]
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[[Category: Labesse G]]
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[[Category: Labesse, G.]]
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[[Category: Mormon J-P]]
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[[Category: Mormon, J P.]]
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[[Category: Trottein F]]
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[[Category: Trottein, F.]]
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[[Category: Vaney MC]]
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[[Category: Vaney, M C.]]
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[[Category: Gst fold]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sat May 3 10:42:58 2008''
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Current revision

Crystal structure of glutathione S-tranferase from Schistosoma mansoni

PDB ID 1u3i

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