1u9s

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[[Image:1u9s.gif|left|200px]]
 
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==Crystal structure of the specificity domain of Ribonuclease P of the A-type==
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The line below this paragraph, containing "STRUCTURE_1u9s", creates the "Structure Box" on the page.
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<StructureSection load='1u9s' size='340' side='right'caption='[[1u9s]], [[Resolution|resolution]] 2.90&Aring;' scene=''>
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== Structural highlights ==
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or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
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<table><tr><td colspan='2'>[[1u9s]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Thermus_thermophilus Thermus thermophilus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1U9S OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1U9S FirstGlance]. <br>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.9&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=BA:BARIUM+ION'>BA</scene></td></tr>
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{{STRUCTURE_1u9s| PDB=1u9s | SCENE= }}
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1u9s FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1u9s OCA], [https://pdbe.org/1u9s PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1u9s RCSB], [https://www.ebi.ac.uk/pdbsum/1u9s PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1u9s ProSAT]</span></td></tr>
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</table>
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'''Crystal structure of the specificity domain of Ribonuclease P of the A-type'''
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==See Also==
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*[[Ribonuclease 3D structures|Ribonuclease 3D structures]]
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__TOC__
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==Overview==
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</StructureSection>
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Large RNA molecules, such as ribozymes, fold with well-defined tertiary structures that are important for their activity. There are many instances of ribozymes with identical function but differences in their secondary structures, suggesting alternative tertiary folds. Here, we report a crystal structure of the 161-nucleotide specificity domain of an A-type ribonuclease P that differs in secondary and tertiary structure from the specificity domain of a B-type molecule. Despite the differences, the cores of the domains have similar three-dimensional structure. Remarkably, the similar geometry of the cores is stabilized by a different set of interactions involving distinct auxiliary elements.
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[[Category: Large Structures]]
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==About this Structure==
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1U9S is a [[Single protein]] structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1U9S OCA].
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==Reference==
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Basis for structural diversity in homologous RNAs., Krasilnikov AS, Xiao Y, Pan T, Mondragon A, Science. 2004 Oct 1;306(5693):104-7. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/15459389 15459389]
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[[Category: Single protein]]
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[[Category: Krasilnikov, A S.]]
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[[Category: Mondragon, A.]]
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[[Category: Pan, T.]]
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[[Category: Xiao, Y.]]
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[[Category: P rna]]
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[[Category: Pre-trna]]
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[[Category: Ribonuclease p rna]]
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[[Category: Ribozyme]]
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[[Category: Rnase p]]
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[[Category: S-domain]]
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[[Category: Specificity domain]]
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[[Category: Thermus thermophilus]]
[[Category: Thermus thermophilus]]
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[[Category: Trna]]
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[[Category: Krasilnikov AS]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sat May 3 10:56:42 2008''
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[[Category: Mondragon A]]
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[[Category: Pan T]]
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[[Category: Xiao Y]]

Current revision

Crystal structure of the specificity domain of Ribonuclease P of the A-type

PDB ID 1u9s

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